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HomoloGene:55645. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   KRT81,  H.sapiens
keratin 81
    NP_002272.2
505 aa
   KRT81,  P.troglodytes
keratin 81
    XP_003313755.1
563 aa
   KRT81,  M.mulatta
keratin 81
    XP_001093214.1
505 aa
   KRT81,  C.lupus
keratin 81
    XP_543657.2
513 aa
   LOC486529,  C.lupus
keratin, type II microfibrillar, component 7C-like
    XP_850166.2
487 aa
   KRT81,  B.taurus
keratin 81
    NP_001069674.1
500 aa
   Krt81,  M.musculus
keratin 81
    NP_001159629.1
481 aa
   Krt81,  R.norvegicus
keratin 81
    NP_001008814.1
541 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Monilethrix.



Publications
Articles associated with genes and sequences of this homology group.

Sequence and expression of human hair keratin genes.
Bowden PE, et al. J Dermatol Sci 7 Suppl, S152-63 (1994).
Keratins of the human hair follicle.
Langbein L & Schweizer J. Int Rev Cytol 243, 1-78 (2005).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Filament (pfam00038)
  Intermediate filament protein.
HR1 (cl00087)
  Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases.
Prefoldin (cl09111)
  Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Krt81 includes H.sapiens KRT81.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 6 species)

 

 

 

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