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HomoloGene:55566. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   CDK9,  H.sapiens
cyclin-dependent kinase 9
    NP_001252.1
372 aa
   CDK9,  P.troglodytes
cyclin-dependent kinase 9
    XP_520277.2
372 aa
   CDK9,  M.mulatta
cyclin-dependent kinase 9
    XP_001094626.1
372 aa
   CDK9,  C.lupus
cyclin-dependent kinase 9
    XP_003639361.2
489 aa
   CDK9,  B.taurus
cyclin-dependent kinase 9
    NP_001014935.2
372 aa
   Cdk9,  M.musculus
cyclin-dependent kinase 9 (CDC2-related kinase)
    NP_570930.1
372 aa
   Cdk9,  R.norvegicus
cyclin-dependent kinase 9
    NP_001007744.1
372 aa
   CDK9,  G.gallus
cyclin-dependent kinase 9
    NP_001006201.1
372 aa
   cdk9,  X.tropicalis
cyclin-dependent kinase 9
    NP_001005448.1
376 aa
   cdk9,  D.rerio
cyclin-dependent kinase 9 (CDC2-related kinase)
    NP_997756.1
393 aa
   Cdk9,  D.melanogaster
Cyclin-dependent kinase 9
    NP_477226.2
404 aa
   AgaP_AGAP008541,  A.gambiae
AgaP_AGAP008541
    XP_314652.2
402 aa
   cdk-9,  C.elegans
cdk-9
    NP_492906.2
478 aa
   cdk9,  S.pombe
cdk9
    NP_595616.1
591 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.
Van Duyne R, et al. J Mol Biol 425, 812-29 (2013).
A role for CDK9-cyclin K in maintaining genome integrity.
Yu DS & Cortez D. Cell Cycle 10, 28-32 (2011).
Selective control of gene expression by CDK9 in human cells.
Garriga J, et al. J Cell Physiol 222, 200-8 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cdk9 includes H.sapiens CDK9 and R.norvegicus Cdk9.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 9 species)
Actinopterygii - bony fishes (13 transcripts, 10 species)
Ascidiacea - tunicates (4 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (15 transcripts, 10 species)
Arachnida - arachnids (2 transcripts, 1 species)
Maxillopoda - crustaceans (2 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Annelida
Hirudinida - segmented worms (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

 

 

 

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