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HomoloGene:4083. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   MRE11A,  H.sapiens
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
    NP_005582.1
708 aa
   MRE11A,  P.troglodytes
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
    XP_001142422.3
710 aa
   MRE11A,  M.mulatta
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
    XP_002799798.1
698 aa
   MRE11A,  C.lupus
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
    XP_005633410.1
708 aa
   GPR83,  B.taurus
G protein-coupled receptor 83
    NP_001179534.1
708 aa
   Mre11a,  M.musculus
meiotic recombination 11 homolog A (S. cerevisiae)
    NP_061206.1
706 aa
   Mre11a,  R.norvegicus
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
    NP_071615.1
706 aa
   MRE11A,  G.gallus
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
    NP_990109.1
700 aa
   mre11a,  X.tropicalis
MRE11 meiotic recombination 11 homolog A
    NP_001107519.1
709 aa
   mre11a,  D.rerio
meiotic recombination 11 homolog A (S. cerevisiae)
    NP_001001407.1
619 aa
   mre11,  D.melanogaster
meiotic recombination 11
    NP_523547.1
620 aa
   AgaP_AGAP006797,  A.gambiae
AgaP_AGAP006797
    XP_308950.4
655 aa
   mre-11,  C.elegans
mre-11
    NP_505736.2
728 aa
   MRE11,  S.cerevisiae
MRE11
    NP_013951.1
692 aa
   KLLA0C06930g,  K.lactis
KLLA0C06930g
    XP_452507.1
694 aa
   AGOS_AFR553C,  E.gossypii
AGOS_AFR553C
    NP_986100.1
674 aa
   rad32,  S.pombe
rad32
    NP_592935.1
649 aa
   MGG_09555,  M.oryzae
MGG_09555
    XP_003712186.1
731 aa
   NCU08730,  N.crassa
NCU08730
    XP_963591.2
786 aa
   MRE11,  A.thaliana
MRE11
    NP_200237.1
720 aa
   Os04g0635900,  O.sativa
Os04g0635900
    NP_001054012.1
705 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Ataxia-telangiectasia-like disorder.



Publications
Articles associated with genes and sequences of this homology group.

Identification of Mre11 as a target for heat radiosensitization.
Dynlacht JR, et al. Radiat Res 176, 323-32 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Mre11_DNA_bind (pfam04152)
  Mre11 DNA-binding presumed domain.
mre11 (TIGR00583)
  DNA repair protein (mre11).
Mre11_DNA_bind (pfam04152)
  Mre11 DNA-binding presumed domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mre11a includes H.sapiens MRE11A and R.norvegicus Mre11a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (9 transcripts, 7 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 8 species)
Arachnida - arachnids (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (10 transcripts, 10 species)
Liliopsida - monocots (7 transcripts, 7 species)
Bryopsida - mosses (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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