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HomoloGene:1603. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   HLA-DQB1,  H.sapiens
major histocompatibility complex, class II, DQ beta 1
    NP_001230890.1
269 aa
   LOC100616520,  P.troglodytes
HLA class II histocompatibility antigen, DQ beta 1 chain-like
    XP_003339166.1
261 aa
   MAMU-DQB1,  M.mulatta
major histocompatibility complex, class II, DQ beta 1
    NP_001127769.1
261 aa
   LOC100856137,  C.lupus
HLA class II histocompatibility antigen, DQ beta 2 chain-like
    XP_003639463.1
269 aa
   DLA-DQB1,  C.lupus
major histocompatibility complex, class II, DQ beta 1
    NP_001014403.1
269 aa
   LA-DQB,  B.taurus
MHC cell surface glycoprotein
    NP_001074392.1
261 aa
   BOLA-DQB,  B.taurus
major histocompatibility complex, class II, DQ beta
    NP_001012694.2
261 aa
   BLA-DQB,  B.taurus
MHC class II antigen
    NP_001029840.2
261 aa
   H2-Ab1,  M.musculus
histocompatibility 2, class II antigen A, beta 1
    NP_996988.2
265 aa
   RT1-Bb,  R.norvegicus
RT1 class II, locus Bb
    NP_001004084.1
263 aa
   hla-drb1,  X.tropicalis
major histocompatibility complex, class II, DR beta 1
    NP_001039259.1
262 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Creutzfeldt-Jakob disease, variant, resistance to.
Multiple sclerosis, susceptibility to.
Insulin-dependent diabetes mellitus-1.



Publications
Articles associated with genes and sequences of this homology group.

Association of HLA-DQB1*0501 with scleroderma and its clinical features in Chinese population.
Zhou XD, et al. Int J Immunopathol Pharmacol 26, 747-51 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MHC_II_beta (pfam00969)
  Class II histocompatibility antigen, beta domain.
MHC_II_beta (cl03042)
  Class II histocompatibility antigen, beta domain.
Ig (cl11960)
  Immunoglobulin domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus H2-Ab1 includes H.sapiens HLA-DQB1 and R.norvegicus RT1-Bb.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (46 transcripts, 12 species)

 

 

 

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