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HomoloGene:10137. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   C9orf72,  H.sapiens
chromosome 9 open reading frame 72
    NP_001242983.1
481 aa
   C9H9orf72,  P.troglodytes
chromosome 9 open reading frame, human C9orf72
    XP_003951454.1
481 aa
   C15H9orf72,  M.mulatta
chromosome 9 open reading frame 72 ortholog
    XP_002800118.1
481 aa
   C11H9orf72,  C.lupus
chromosome 11 open reading frame, human C9orf72
    XP_005626755.1
481 aa
   C8H9orf72,  B.taurus
chromosome 8 open reading frame, human C9orf72
    NP_001096558.1
481 aa
   3110043O21Rik,  M.musculus
RIKEN cDNA 3110043O21 gene
    NP_001074812.1
481 aa
   RGD1359108,  R.norvegicus
similar to RIKEN cDNA 3110043O21
    NP_001007703.1
481 aa
   C9ORF72,  G.gallus
chromosome Z open reading frame, human C9orf72
    XP_424945.2
481 aa
   zgc:100846,  D.rerio
zgc:100846
    NP_991166.1
462 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Basal ganglia involvement in amyotrophic lateral sclerosis.
Bede P, et al. Neurology 81, 2107-15 (2013).
C9ORF72 repeat expansions in cases with previously identified pathogenic mutations.
van Blitterswijk M, et al. Neurology 81, 1332-41 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
C9orf72-like (pfam15019)
  C9orf72-like protein family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus 3110043O21Rik includes H.sapiens C9orf72 and R.norvegicus RGD1359108.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 9 species)
Actinopterygii - bony fishes (11 transcripts, 9 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

 

 

 

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