1: HomoloGene:55620. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

   DRP2,  Homo sapiens
dystrophin related protein 2
    NP_001930.2
957 aa
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   DRP2,  Canis lupus familiaris
dystrophin related protein 2
    XP_538105.2
957 aa
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   DRP2,  Bos taurus
dystrophin related protein 2
    XP_617584.2
957 aa
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   Drp2,  Mus musculus
dystrophin related protein 2
    NP_034208.1
957 aa
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   Drp2,  Rattus norvegicus
dystrophin related protein 2
    NP_076461.1
957 aa
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   drp2,  Danio rerio
dystrophin related protein 2
    NP_001074036.1
866 aa
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   LOC100002550,  Danio rerio
similar to dystrophin related protein 2
    XP_001342308.1
806 aa
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Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenrate Alignments




PubMed
Articles associated with genes and sequences of this entry plus additional related articles.

 
Bisgaard CF, et al.
Proteomic investigation of the ventral rat hippocampus links DRP-2 to escitalopram treatment resistance and SNAP to stress resilience in the chronic mild stress model of depression. J Mol Neurosci 32, 132-44(2007).
 
Ujike H, et al.
Association study of the dihydropyrimidinase-related protein 2 gene and methamphetamine psychosis. Ann N Y Acad Sci 1074, 90-6(2006).
 
Suk Danik J, et al.
Influence of genetic variation in the C-reactive protein gene on the inflammatory response during and after acute coronary ischemia. Ann Hum Genet 70, 705-16(2006).
 
Nakata K & Ujike H.
[The human dihydropyrimidinase-related protein 2 (DRP-2) gene on chromosome 8p21 is associated with paranoid-type schizophrenia] Nihon Shinkei Seishin Yakurigaku Zasshi 24, 33-7(2004).
 
Nakata K, et al.
The human dihydropyrimidinase-related protein 2 gene on chromosome 8p21 is associated with paranoid-type schizophrenia. Biol Psychiatry 53, 571-6(2003).
 

 


Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.

 
 
 
WW (cl00157)
  Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...
 
ZZ (cl00295)
  Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have...
 
SPEC (cl02488)
  Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences...



Related Homology Resources
Links to curated and computed homology information found in other databases.

 
Orthology group for M.musculus Drp2 includes H.sapiens DRP2 and R.norvegicus Drp2.



UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.

 
Dystrophin related protein 2
 
Hypothetical protein LOC100002550
 
Similar to dystrophin-related protein 2 A-form splice
 
Dystrophin related protein 2
 
Dystrophin related protein 2
Dystrophin related protein 2
 
Dystrophin related protein 2
 
Transcribed locus, strongly similar to NP_004005.1 dystrophin Dp116 isoform ...
 
Dystrophin related protein 2