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HomoloGene:52252. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

   PLA2G4D,  H.sapiens
phospholipase A2, group IVD (cytosolic)
818 aa
   PLA2G4D,  P.troglodytes
phospholipase A2, group IVD (cytosolic)
809 aa
   PLA2G4D,  M.mulatta
phospholipase A2, group IVD (cytosolic)
817 aa
   PLA2G4D,  C.lupus
phospholipase A2, group IVD (cytosolic)
812 aa
   PLA2G4D,  B.taurus
phospholipase A2, group IVD (cytosolic)
816 aa
   Pla2g4d,  M.musculus
phospholipase A2, group IVD
825 aa
   Pla2g4d,  R.norvegicus
phospholipase A2, group IVD (cytosolic)
825 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

A family based study of the genetic association between the PLA2G4D gene and schizophrenia.
Tao R, et al. Prostaglandins Leukot Essent Fatty Acids 73, 419-22 (2005).
HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes.
Mavoungou E, et al. J Acquir Immune Defic Syndr Hum Retrovirol 16, 1-9 (1997).
Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death.
Schröder HC, et al. Neurotoxicology 19, 683-8 (1998).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Patatin_and_cPLA2 (cl11396)
  Patatins and Phospholipases.
C2 (cl14603)
  C2 domain.
Patatin_and_cPLA2 (cl11396)
  Patatins and Phospholipases.
C2 (cl14603)
  C2 domain.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pla2g4d includes H.sapiens PLA2G4D and R.norvegicus Pla2g4d.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (4 transcripts, 4 species)




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