Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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SGCD, Homo sapiens
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
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NP_000328.2
290 aa |
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SGCD, Pan troglodytes
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
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XP_001134824.1
289 aa |
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SGCD, Canis lupus familiaris
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
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XP_854897.1
382 aa |
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LOC517059, Bos taurus
similar to delta-sarcoglycan |
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XP_001787327.1
289 aa |
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Sgcd, Mus musculus
sarcoglycan, delta (dystrophin-associated glycoprotein) |
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NP_036021.1
289 aa |
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Sgcd, Rattus norvegicus
sarcoglycan, delta (dystrophin-associated glycoprotein) |
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XP_573076.2
289 aa |
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SGCD, Gallus gallus
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
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XP_414572.1
292 aa |
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sgcd, Danio rerio
sarcoglycan, delta (dystrophin-associated glycoprotein) |
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NP_001001816.1
289 aa |
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Scgdelta, Drosophila melanogaster
Sarcoglycan delta |
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NP_525039.1
404 aa |
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AgaP_AGAP000073, Anopheles gambiae
AGAP000073-PA |
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XP_311082.4
386 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Homo sapiens |
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Muscular dystrophy, limb-girdle, type 2F. |
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Cardiomyopathy, dilated, 1L. |
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Mus musculus |
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Muscle phenotype. |
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Life span-post-weaning/aging. |
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Homeostasis/metabolism phenotype. |
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Cardiovascular system phenotype. The observable morphological and physiological characteristics of the mammalian heart, blood vessels, or circulatory system that are manifested through development and lifespan. |
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Other phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Bauer R, et al.Steroid treatment causes deterioration of myocardial function in the {delta}-sarcoglycan-deficient mouse model for dilated cardiomyopathy. Cardiovasc Res 79, 652-61(2008). |
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Allikian MJ, et al.Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants. Hum Mol Genet 16, 2933-43(2007). |
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Honda T, et al.Impact of delta-sarcoglycan gene polymorphism on the occurrence of coronary spastic angina in Japanese patients with hypertrophic cardiomyopathy. Circ J 71, 1263-7(2007). |
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Milner DJ & Kaufman SJ.Alpha7beta1 integrin does not alleviate disease in a mouse model of limb girdle muscular dystrophy type 2F. Am J Pathol 170, 609-19(2007). |
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Nomura T, et al.Skeletal myosphere-derived progenitor cell transplantation promotes neovascularization in delta-sarcoglycan knockdown cardiomyopathy. Biochem Biophys Res Commun 352, 668-74(2007). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Sgcd includes H.sapiens SGCD and R.norvegicus Sgcd. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Similar to delta-sarcoglycan |
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Transcribed locus, weakly similar to NP_001001816.1 sarcoglycan, delta (dyst... |
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Sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
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Sarcoglycan, delta (dystrophin-associated glycoprotein) |
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Sarcoglycan delta |
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Sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
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Clone CGX41-H08 mRNA sequence |
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Sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
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Similar to delta-sarcoglycan isoform 2 |
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Sarcoglycan, delta (dystrophin-associated glycoprotein) |
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Transcribed locus, moderately similar to NP_001001816.1 sarcoglycan, delta (... |
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Sarcoglycan, delta (dystrophin-associated glycoprotein) |
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Transcribed locus, strongly similar to NP_036021.1 sarcoglycan, delta (dystr... |
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