Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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SNTA1, Homo sapiens
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) |
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NP_003089.1
505 aa |
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SNTA1, Canis lupus familiaris
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) |
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XP_863072.1
515 aa |
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SNTA1, Bos taurus
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) |
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NP_001069366.1
505 aa |
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Snta1, Mus musculus
syntrophin, acidic 1 |
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NP_033254.1
503 aa |
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Snta1, Rattus norvegicus
syntrophin, acidic 1 |
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XP_342549.2
499 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Mus musculus |
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Nervous system phenotype. |
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Muscle phenotype. |
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Homeostasis/metabolism phenotype. |
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Behavior/neurological phenotype. The observable actions or reactions of mammalian organisms that are manifested through development and lifespan. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Wu G, et al.alpha-1-syntrophin mutation and the long-QT syndrome: a disease of sodium channel disruption. Circ Arrhythm Electrophysiol 1, 193-201(2008). |
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Bragg AD, et al.Assembly of a perivascular astrocyte protein scaffold at the mammalian blood-brain barrier is dependent on alpha-syntrophin. Glia 53, 879-90(2006). |
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Puwarawuttipanit W, et al.Differential effect of alpha-syntrophin knockout on aquaporin-4 and Kir4.1 expression in retinal macroglial cells in mice. Neuroscience 137, 165-75(2006). |
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Yan J, et al.Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin. EMBO J 24, 3985-95(2005). |
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Harris BZ, et al.Role of electrostatic interactions in PDZ domain ligand recognition. Biochemistry 42, 2797-805(2003). |
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Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Snta1 includes H.sapiens SNTA1 and R.norvegicus Snta1. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic compone... |
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Syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic compone... |
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Similar to LOC496157 protein |
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Transcribed locus, moderately similar to XP_342549.2 PREDICTED: similar to A... |
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Syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic compone... |
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Syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic compone... |
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Syntrophin, acidic 1 |
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Similar to Snta1 protein |
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Syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic compone... |
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Syntrophin, acidic 1 |
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Transcribed locus, strongly similar to XP_342549.2 PREDICTED: similar to Alp... |
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Hypothetical protein MGC147484 |
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Hypothetical LOC496157 |
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