Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.
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Proteins
Proteins used in sequence comparisons and their conserved domain architectures.
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SGCG, Homo sapiens
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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NP_000222.1
291 aa |
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SGCG, Pan troglodytes
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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XP_001151077.1
291 aa |
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SGCG, Canis lupus familiaris
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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NP_001014298.1
291 aa |
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SGCG, Bos taurus
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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NP_001068712.1
291 aa |
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Sgcg, Mus musculus
sarcoglycan, gamma (dystrophin-associated glycoprotein) |
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NP_036022.1
291 aa |
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Sgcg, Rattus norvegicus
sarcoglycan, gamma (dystrophin-associated glycoprotein) |
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NP_001006994.1
292 aa |
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SGCG, Gallus gallus
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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XP_417139.2
291 aa |
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sgcg, Danio rerio
sarcoglycan, gamma |
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NP_001003748.1
292 aa |
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Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.
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Homo sapiens |
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Muscular dystrophy, limb-girdle, type 2C. |
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Mus musculus |
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Muscle phenotype. |
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Life span-post-weaning/aging. |
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Lethality-postnatal. |
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Homeostasis/metabolism phenotype. |
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Growth/size phenotype. |
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Cellular phenotype. |
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Cardiovascular system phenotype. The observable morphological and physiological characteristics of the mammalian heart, blood vessels, or circulatory system that are manifested through development and lifespan. |
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Behavior/neurological phenotype. The observable actions or reactions of mammalian organisms that are manifested through development and lifespan. |
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Skeleton phenotype. |
PubMed
Articles associated with genes and sequences of this entry plus additional related articles.
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Khadilkar SV, et al.Spectrum of mutations in sarcoglycan genes in the Mumbai region of western India: high prevalence of 525del T. Neurol India 57, 406-10(2009). |
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Duncan DR, et al.A novel mutation in two families with limb-girdle muscular dystrophy type 2C. Neurology 67, 167-9(2006). |
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Griffin MA, et al.gamma-Sarcoglycan deficiency increases cell contractility, apoptosis and MAPK pathway activation but does not affect adhesion. J Cell Sci 118, 1405-16(2005). |
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Georgieva B, et al.C283Y gamma-sarcoglycan gene mutation in the Bulgarian Roma (Gypsy) population: prevalence study and carrier screening in a high-risk community. Clin Genet 66, 467-72(2004). |
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Vermeer S, et al.Novel mutations in three patients with LGMD2C with phenotypic differences. Pediatr Neurol 30, 291-4(2004). |
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Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
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Related Homology Resources
Links to curated and computed homology information found in other databases.
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Orthology group for M.musculus Sgcg includes H.sapiens SGCG and R.norvegicus Sgcg. |
UniGene
Links to groups of transcribed sequences established by tblastn searching of UniGene.
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Sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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Sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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Hypothetical protein LOC100002105 |
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Hypothetical LOC555004 |
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Similar to gamma-sarcoglycan |
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Sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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Transcribed locus, moderately similar to XP_692513.1 PREDICTED: similar to g... |
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Sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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Sarcoglycan, gamma (dystrophin-associated glycoprotein) |
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Sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
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Transcribed locus, weakly similar to NP_001003748.1 sarcoglycan, gamma [Dani... |
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Sarcoglycan, gamma (dystrophin-associated glycoprotein) |
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Transcribed locus, moderately similar to NP_036022.1 sarcoglycan, gamma (dys... |
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Gamma sarcoglycan |
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