GTR Home > Tests > SDHB-Related Hereditary Paraganglioma-Pheochromocytoma Syndrome

Overview

Test order codeHelp: SDHB

Test name

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SDHB-Related Hereditary Paraganglioma-Pheochromocytoma Syndrome (SDHB)

Purpose of the test

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This is a clinical test intended for Help: Diagnosis, Mutation Confirmation, Pre-symptomatic

Condition

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1 condition tested. Click Indication tab for more information.

Methodology

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Molecular Genetics
ESequence analysis of select exons
Next-Generation (NGS)/Massively parallel sequencing (MPS)
  • Illumina HiSeq™2000 system
CSequence analysis of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)
  • Illumina HiSeq™2000 system

Summary of what is tested

1 genes and variants. Click Methodology tab for more information.

Genes

Clinical validity

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Not provided

Clinical utility

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Not provided

How to order

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Refer to list of tests and instructions on website
Order URL Help: http://www.exeterlaboratory.com/genetics/phaeochromocytoma-paraganglioma/

Practice guidelines

  • Endocrine Society, 2014
    Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.
  • ASCO, 2014
    American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers.
  • KCRNC, 2013
    Canadian guideline on genetic screening for hereditary renal cell cancers.
  • NANETS, 2010
    The NANETS Consensus Guideline for the Diagnosis and Management of Neuroendocrine Tumors: Pheochromocytoma, Paraganglioma & Medullary Thyroid Cancer

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