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SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4

Also known as: GLUT4

Summary

This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]

Genomic context

Location:
17p13
Sequence:
Chromosome: 17; NC_000017.11 (7281735..7288048)
Total number of exons:
11

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