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RAG1 recombination activating 1

Also known as: RAG-1; RNF74

Summary

The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases. [provided by RefSeq, Jul 2008]

Genomic context

Location:
11p13
Sequence:
Chromosome: 11; NC_000011.10 (36510366..36579762)
Total number of exons:
4

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