GTR Home > Genes

H19 H19, imprinted maternally expressed transcript (non-protein coding)

Also known as: ASM; BWS; WT2; ASM1; D11S813E; LINC00008; NCRNA00008


This gene is located in an imprinted region of chromosome 11 near the insulin-like growth factor 2 (IGF2) gene. This gene is only expressed from the maternally-inherited chromosome, whereas IGF2 is only expressed from the paternally-inherited chromosome. The product of this gene is a long non-coding RNA which functions as a tumor suppressor. Mutations in this gene have been associated with Beckwith-Wiedemann Syndrome and Wilms tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Copy number response

Copy number response

No evidence available (Last evaluated (2012-03-22)

ClinGen Genome Curation Page

No evidence available (Last evaluated (2012-03-22)

ClinGen Genome Curation Page

Genomic context

Chromosome: 11; NC_000011.10 (1995176..1997835, complement)
Total number of exons:


  • ClinVar
    Related medical variations
  • dbVar
    Link from Gene to dbVar
  • H19 @ LOVD
  • MedGen
    Related information in MedGen
  • OMIM
    Links between OMIM and Gene are calculated by Gene based on MIM numbers included in the summary and phenotype sections of the Gene record.
  • PubMed (OMIM)
    Links are provided when Gene has a link to a record in OMIM, and OMIM explicitly cites these publications in PubMed.
  • RefSeq RNAs
    Link to Nucleotide RefSeq RNAs
  • RefSeqGene
    Link to Nucleotide RefSeqGenes
  • SNP: GeneView
    SNPs linked from GeneView

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.