GTR Home > Conditions/Phenotypes > Charcot-Marie-Tooth disease type 2P

Disease characteristics

Excerpted from the GeneReview: Charcot-Marie-Tooth Neuropathy Type 2
Charcot-Marie-Tooth hereditary neuropathy type 2 (CMT2) is an axonal (non-demyelinating) peripheral neuropathy characterized by distal muscle weakness and atrophy, mild sensory loss, and normal or near-normal nerve conduction velocities. CMT2 is clinically similar to CMT1, although typically less severe. Peripheral nerves are not enlarged or hypertrophic. The subtypes of CMT2 are similar clinically and distinguished only by molecular genetic findings.

Available tests

2 tests are in the database for this condition. Compare labs offering these tests.

Check Associated genes and Related conditions for additional relevant tests.

Associated genes

  • Also known as: UNQ6496/PRO21356, CMT2P, RIFLE, TAL, LRSAM1
    Summary: leucine rich repeat and sterile alpha motif containing 1

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