GTR Home > Conditions/Phenotypes > Inflammatory bowel disease 1


A condition in which the gastrointestinal tract is inflamed over a long period of time. Regional enteritis usually affects the small intestine and colon. Symptoms include fever, diarrhea, stomach cramps, vomiting, and weight loss. Regional enteritis increases the risk of colorectal cancer and small intestine cancer. It is a type of inflammatory bowel disease (IBD). [from NCI]

Associated genes

  • Also known as: BSF2, HGF, HSF, IFNB2, IL-6, IL6
    Summary: interleukin 6

  • Also known as: ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1, NOD2
    Summary: nucleotide-binding oligomerization domain containing 2

Clinical features

  • Diarrhea
  • Weight loss
  • Abdominal pain
  • Intestinal obstruction
  • Recurrent aphthous stomatitis

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