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GTR Home > Conditions/Phenotypes > Cutaneous neuroendocrine carcinoma

Cutaneous neuroendocrine carcinoma

Synonyms
Merkel cell cancer; Merkel cell carcinoma; Merkel cell skin cancer; Merkle tumors
Modes of inheritance
Not genetically inherited (Orphanet)

Summary

A malignant cutaneous tumor of the elderly that is characterized by an aggressive course with regional nodal involvement, distant metastases and a high rate of recurrence. Most patients present with rapidly growing, painless, firm, non-tender, dome-shaped red, occasionally ulcerated skin nodules, which have a red or bluish color, measuring up to several centimeters, on predominantly sun-exposed areas of the body. The overlying skin is smooth and shiny, sometimes exhibiting ulcerative, acneiform or telangiectatic features. [from HPO]

Reviews

Clinical resources

Practice guidelines

  • NCCN, 2023
    NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Merkel Cell Carcinoma, 2023

Consumer resources

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