Literature
PubMed
PubMed® comprises more than 37 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.
Featured Bookshelf titles
Drug Therapy for Early Rheumatoid Arthritis
A Systematic Review Update
Literature databases
Books and reports
Ontology used for PubMed indexing
Books, journals and more in the NLM Collections
Scientific and medical abstracts/citations
Full-text journal articles
Data
Genes
Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution
Collected information about gene loci
Functional genomics studies
Gene expression and molecular abundance profiles
Homologous genes sets for selected organisms
Sequence sets from phylogenetic and population studies
Proteins
Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites
Conserved protein domains
Protein sequences grouped by identity
Protein sequences
Models representing homologous proteins with a common function
Experimentally-determined biomolecular structures
BLAST
A tool to find regions of similarity between biological sequences
Search nucleotide sequence databases
Search protein sequence databases
Search protein databases using a translated nucleotide query
Search translated nucleotide databases using a protein query
Find primers specific to your PCR template
Genomes
Genome sequence assemblies, large-scale functional genomics data, and source biological samples
Genome assembly information
Museum, herbaria, and other biorepository collections
Biological projects providing data to NCBI
Descriptions of biological source materials
Genome sequencing projects by organism
DNA and RNA sequences
High-throughput sequence reads
Taxonomic classification and nomenclature
Clinical
Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments
Privately and publicly funded clinical studies conducted around the world
Human variations of clinical significance
Genotype/phenotype interaction studies
Short genetic variations
Genome structural variation studies
Genetic testing registry
Medical genetics literature and links
Online mendelian inheritance in man
PubChem
Repository of chemical information, molecular pathways, and tools for bioactivity screening
Bioactivity screening studies
Chemical information with structures, information and links
Molecular pathways with links to genes, proteins and chemicals
Deposited substance and chemical information
News
Research news
Experimental gene therapy for giant axonal neuropathy shows promise in NIH clinical trial
Treatment for rare childhood disease was well tolerated and slowed loss of motor function.
How Cloud Labs and Remote Research Shape Science
Remote research via cloud labs makes it possible for scientists to conduct complex experiments from a distance.
NIH studies find severe symptoms of “Havana Syndrome,” but no evidence of MRI-detectable brain injury or biological abnormalities
Compared to healthy volunteers, affected U.S. government personnel did not exhibit differences that would explain symptoms.
Recent blog posts
“Computers don’t diagnose the same way that doctors do”NLM Lecture Explored How a Cancer Diagnosis Can Help Illustrate …
How can cancer help us understand algorithmic bias? At this year’s NLM Science, Technology, and Society Lecture, journalist and AI ethics expert Meredith Broussard shared how her personal experience with breast cancer can help illuminate the potential impact that racial and gender bias can have on the use of AI in medical contexts.
Welcoming Internet Pioneer Vint Cerf for Rall Cultural Lecture on AI in Biomedical Research
Last week it was my pleasure to welcome to NIH Vinton “Vint” Cerf, a pioneer of the digital world widely known as one of the “fathers of the internet,” to speak at our annual J. Edward Rall Cultural Lecture. We had a lively fireside chat focusing on “The Promises and Perils of AI in Biomedical Research and Health Care Delivery” that included discussions on topics like improving data collection, ensuring broad representativeness of the data being used to train AI and machine learning, expanding clinical research, and offering advice for scientists just starting out. It was an insightful, eye-opening conversation on a topic close to my heart. As NIH Director, I very much hope to deliver evidence-based health care to all people, and I’m excited about how AI and machine learning can help us advance toward that goal.
Appreciating the Distinction: Clinical Informatics Research vs. Clinical Research Informatics
NLM funds grants related to both Clinical Informatics Research and Clinical Research Informatics—two fields that sound similar but are distinct in the ways they contribute to advancing health care delivery and patient outcomes. NLM’s Dr. Allison Dennis discusses how these concepts relate and how researchers can apply to related funding opportunities.