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    LIF-AS2 LIF antisense RNA 2 [ Homo sapiens (human) ]

    Gene ID: 91370, updated on 10-Oct-2023

    Summary

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    Official Symbol
    LIF-AS2provided by HGNC
    Official Full Name
    LIF antisense RNA 2provided by HGNC
    Primary source
    HGNC:HGNC:28298
    See related
    Ensembl:ENSG00000268812 AllianceGenome:HGNC:28298
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TP53LC08
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    Genomic context

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    Location:
    22q12.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (30246210..30246993)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (30709528..30710311)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (30642199..30642982)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene HORMA domain containing 2 Neighboring gene uncharacterized LOC105372988 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18827 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr22:30601719-30602918 Neighboring gene Sharpr-MPRA regulatory region 10236 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:30610529-30611063 Neighboring gene CRISPRi-validated cis-regulatory element chr22.1257 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:30617260-30617890 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30618871-30619372 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30619373-30619872 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:30622687-30623483 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:30624775-30625710 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30627593-30628226 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30631328-30631830 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30637625-30638293 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30640698-30641198 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30648163-30648928 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30648929-30649693 Neighboring gene LIF antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13602 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30650183-30650684 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30650685-30651184 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13603 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:30653067-30653669 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:30653670-30654271 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30656529-30657028 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30659020-30659819 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30659820-30660618 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18829 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18830 Neighboring gene LIF interleukin 6 family cytokine Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:30672215-30672804 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30673676-30674204 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:30674205-30674733 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13605 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13604 Neighboring gene oncostatin M Neighboring gene cytosolic arginine sensor for mTORC1 subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TP53-inducible putative long noncoding RNAs encode functional polypeptides that suppress cell proliferation. Xu W, et al. Genome Res, 2022 Jun. PMID 35609991, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    Genotypes

    General gene information

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    Clone Names

    • MGC20647

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_148946.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      BC014233
      Related
      ENST00000608354.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      30246210..30246993
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      30709528..30710311
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_052856.1: Suppressed sequence

      Description
      NM_052856.1: This RefSeq was permanently suppressed because the gene is not thought to be protein-coding.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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