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| Status |
Public on Jul 27, 2011 |
| Title |
C-peptide regulates early transcription in rat proximal tubular cells |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
C-peptide exerts beneficial effects on glomerular hyperfiltration in type I diabetic patients. As C-peptide localizes to the nucleus, we investigated the transcriptional activities of C-peptide in proximal tubular cells isolated from diabetic rats.
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| Overall design |
Two groups of proximal tubular cells isolated from type I diabetic rats: 1 treated with C-peptide, and 1 untreated. 2-3 replicates per group.
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| Contributor(s) |
Lindahl E, Nordquist L, Müller P, El Agha E, Friederich M, Dahlman-Wright K, Palm F, Jörnvall H |
| Citation(s) |
21618400 |
| Submission date |
Oct 13, 2010 |
| Last update date |
Nov 06, 2013 |
| Contact name |
Emma Lindahl |
| E-mail(s) |
emmalindahl@gmail.com
|
| Organization name |
Karolinska Institutet
|
| Street address |
Scheeles väg 2
|
| City |
Stockholm |
| ZIP/Postal code |
17177 |
| Country |
Sweden |
| |
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| Platforms (1) |
| GPL6247 |
[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (5)
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| Relations |
| BioProject |
PRJNA132257 |
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