|
| Status |
Public on Jun 23, 2019 |
| Title |
JMJD6 and NMYC binding examined by ChIP-seq in NMYC overexpressing CHP134 human neuroblastoma cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
JMJD6 (also known as PTDSR) is an important oncogene that is upregulated in 17q21-ter gained neuroblastoma.It plays a role in E2F and N-Myc-regulated gene pathways and neuroblastoma tumorigenesis
Using ChIP-Seq, we profiled JMJD6 and NMYC binding in the NMYC overexpressing neuroblastoma cell line.
We identified the genomic location of JMJD6 and NMYC binding peaks across the human genome.
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| |
|
| Overall design |
Identification of JMJD6 and NMYC protein binding locations on a genomic scale in CHP-134 neuroblastoma cells.
|
| |
|
| Contributor(s) |
Wong M, Poulos R, Wong J, Liu T |
| Citation(s) |
31346162 |
| Submission date |
Apr 10, 2019 |
| Last update date |
Sep 23, 2019 |
| Contact name |
matthew kwok kei wong |
| E-mail(s) |
MWong@ccia.org.au
|
| Organization name |
Children's Cancer Institute
|
| Department |
histone modification group
|
| Street address |
Lowy cancer centre, University of New South Wales
|
| City |
Sydney |
| State/province |
New South Wales |
| ZIP/Postal code |
2031 |
| Country |
Australia |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (6)
|
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| This SubSeries is part of SuperSeries: |
| GSE113140 |
JMJD6 gene gain is a tumorigenic factor and therapeutic target in neuroblastoma |
|
| Relations |
| BioProject |
PRJNA531892 |
| SRA |
SRP191800 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE129588_JMJD6_NT_common_peaks.bed.gz |
4.9 Kb |
(ftp)(http) |
BED |
| GSE129588_NMYC_JMJD6_NT_common_peaks.bed.gz |
2.1 Kb |
(ftp)(http) |
BED |
| GSE129588_NMYC_NT_common_peaks.bed.gz |
86.0 Kb |
(ftp)(http) |
BED |
| GSE129588_enhancers_BOTH-NT_merged.bed.gz |
1.8 Kb |
(ftp)(http) |
BED |
| GSE129588_enhancers_JMJD6-NT_merged.bed.gz |
2.6 Kb |
(ftp)(http) |
BED |
| GSE129588_enhancers_NMYC-NT_merged.bed.gz |
108.3 Kb |
(ftp)(http) |
BED |
| GSE129588_promoters_1kb_BOTH-NT_merged.bed.gz |
1.2 Kb |
(ftp)(http) |
BED |
| GSE129588_promoters_1kb_JMJD6-NT_merged.bed.gz |
2.4 Kb |
(ftp)(http) |
BED |
| GSE129588_promoters_1kb_NMYC-NT_merged.bed.gz |
63.5 Kb |
(ftp)(http) |
BED |
| GSE129588_superenhancers_BOTH-NT_merged.bed.gz |
282 b |
(ftp)(http) |
BED |
| GSE129588_superenhancers_JMJD6-NT_merged.bed.gz |
341 b |
(ftp)(http) |
BED |
| GSE129588_superenhancers_NMYC-NT_merged.bed.gz |
4.3 Kb |
(ftp)(http) |
BED |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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