Severe Acute Respiratory Syndrome (SARS)	SARS Home

NP_828870.1 AVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDV SARS-CoV
NP_840010.1 AAGMCVVCGSQTVLRCGDCLRRPLLCTKCAYDHVMGTKHKFIMSITPYVCSFNGCNVNDV TGEV    
NP_839966.1 SAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVIGTTHKFILAITPYVCCASDCGVNDV PEDV    
NP_742139.1 SVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDV BCoV    
NP_835353.1 AAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVFGTDHKFILAITPYVCNTSGCNVNDV HCoV-229E
NP_740617.1 SVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNSPGCDVNDV MHV     
NP_740630.1 SCGVCVVCNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYICSQLGCGEADV IBV     
Consensus   ulGlCVVCsSQTsLRCGpClR+PhLCoKChYDHVhuTpHKhlLulpPYVCp.sGCsVpDV




NP_828870.1 TQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDY SARS-CoV
NP_840010.1 TKLFLGGLSYYCMNHKPQLSFPLCANGNVFGLYKSSAVGSEAVEDFNKLAVSDWTNVEDY TGEV    
NP_839966.1 TKLYLGGLSYWCHEHKPRLAFPLCSAGNVFGLYKNSATGSPDVEDFNRIATSDWTDVSDY PEDV    
NP_742139.1 TKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDY BCoV    
NP_835353.1 TKLYLGGLNYYCVDHKPHLSFPLCSAGNVFGLYKSSALGSMDIDVFNKLSTSDWSDIRDY HCoV-229E
NP_740617.1 TKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASCKWTEVDDY MHV     
NP_740630.1 TKLYLGGMSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLATTNWSIVEPY IBV     
Consensus   TKLYLGGhSYaC.pHKPphSF.Lh.sG.VFGLYKpohsGS..l=DFNplAoocWoplpDY




NP_828870.1 ILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNY SARS-CoV
NP_840010.1 KLANNVKESLKIFAAETVKAKEESVKSEYAYAVLKEVIGPKEIVLQWEASKTKPPLNRNS TGEV    
NP_839966.1 RLANDVKDSLRLFAAETIKAKEESVKSSYACATLHEVVGPKELLLKWEVGRPKPPLNRNS PEDV    
NP_742139.1 ILANECTERLKLFAAETQKATEEAFKQSYASATIQEIVSERELILSWEIGKVKPPLNKNY BCoV    
NP_835353.1 KLANDAKESLRLFAAETVKAKEESVKSSYAYATLKEIVGPKELLLLWESGKAKPPLNRNS HCoV-229E
NP_740617.1 VLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWEIGKVRPPLNKNY MHV     
NP_740630.1 ILANRCSDSLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPGKTRPPLNRNY IBV     
Consensus   bLANphp=pL+lFAAET.KApEEshKppYA.Apl+Ellus+ELlLpWE.GKs+PPLN+N.




NP_828870.1 VFTGYRVTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPT SARS-CoV
NP_840010.1 VFTCFQISKDTKIQLGEFVFEQSEYGSDSVYYKSTSTYKLTPGMIFVLTSHNVSPLKAPI TGEV    
NP_839966.1 VFTCYHITKNTKFQIGEFVFEKAEYDNDAVTYKTTATTKLVPGMVFVLTSHNVQPLRAPT PEDV    
NP_742139.1 VFTGYHFTKNGKTVLGEYVFDKSEL-TNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPT BCoV    
NP_835353.1 VFTCFQITKDSKFQVGEFVFEKVDYGSDTVTYKSTATTKLVPGMLFILTSHNVAPLRAPT HCoV-229E
NP_740617.1 VFTGYHFTNNGKTVLGEYVFDKSEL-TNGVYYRATTTYKLSVGDVFILTSHAVSSLSAPT MHV     
NP_740630.1 VFTGYHFTRTSKVQLGDFTFEKGEG-KDVVYYKATSTAKLSVGDIFVLTSHNVVSLVAPT IBV     
Consensus   VFTsaphT+psK..lGEasF=Ku=h ppsV.Y+uTsT.KLssG.lFlLTSHpV.sLpAPT




NP_828870.1 LVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYY SARS-CoV
NP_840010.1 LVNQEKYNTISKLYPVFNIAEAYNTLVPYYQMIGKQKFTTIQGPPGSGKSHCVIGLGLYY TGEV    
NP_839966.1 IANQERYSTIHKLHPAFNIPEAYSSLVPYYQLIGKQKITTIQGPPGSGKSHCVIGLGLYY PEDV    
NP_742139.1 LVPQENYSSIR-FASVYSVLETFQNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYY BCoV    
NP_835353.1 MANQEKYSTIYKLHPSFNVSDAYANLVPYYQLIGKQRITTIQGPPGSGKSHCSIGIGVYY HCoV-229E
NP_740617.1 LVPQENYTSIR-FASVYSVPETFQNNVPNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYY MHV     
NP_740630.1 LCPQQTFSRFVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSHFAIGLAVYF IBV     
Consensus   llsQEpYppI. h.sshpls=sa.p.Vs.YQ.lGbp+hoTlQGPPGoGKSHhlIGLulYY




NP_828870.1 PSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCT SARS-CoV
NP_840010.1 PQARIVYTACSHAAVDALCEKAAKNFNVDRCSRIIPQRIRVDCYTGFKPNNTNAQYLFCT TGEV    
NP_839966.1 PGARIVFTACSHAAVDSLCVKASTAYSNDKCSRIIPQRARVECYDGFKSNNTSAQYLFST PEDV    
NP_742139.1 CTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVFTT BCoV    
NP_835353.1 PGARIVFTACSHAAVDSLCAKAVTAYSVDKCTRIIPARARVECYSGFKPNNNSAQYVFST HCoV-229E
NP_740617.1 CTARVVYTAASHAAVDALCEKAHKFLNINDCTRIVPAKVRVDCYDKFKVNDTTRKYVFTT MHV     
NP_740630.1 SSARVVFTACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKANDTGKKYIFST IBV     
Consensus   ssARlVaTAhSHAAVDuLC.KA.phhplpcCoRIlP.+lRV=Cap.FKsNpTs.pYlFoT




NP_828870.1 VNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEP SARS-CoV
NP_840010.1 VNALPEASCDIVVVDEVSMCTNYDLSVINSRLSYKHIVYVGDPQQLPAPRTLINKGVLQP TGEV    
NP_839966.1 VNALPECNADIVVVDEVSMCTNYDLSVINQRISYRHVVYVGDPQQLPAPRVMISRGTLEP PEDV    
NP_742139.1 INALPEMVTDIVVVDEVSMLTNYELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEP BCoV    
NP_835353.1 VNALPEVNADIVVVDEVSMCTNYDLSVINQRISYKHIVYVGDPQQLPAPRVLISKGVMEP HCoV-229E
NP_740617.1 INALPELVTDIIVVDEVSMLTNYELSVINSRVSAKHYVYIGDPAQLPAPRVLLNKGTLEP MHV     
NP_740630.1 INALPEVSCDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRTLLN-GSLSP IBV     
Consensus   lNALPEhssDIlVVDEVSMhTNY=LSVIN.Rlph+HhVYlGDP.QLPAPRsLlp+GsLpP




NP_828870.1 EYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKG- SARS-CoV
NP_840010.1 QDYNVVTKRMCTLGPDVFLHKCYRCPAEIVKTVSALVYENKFVPVNPESKQCFKMFVKG- TGEV    
NP_839966.1 KDYNVVTQRMCALKPDVFLHKCYRCPAEIVRTVSEMVYENQFIPVHPDSKQCFKIFCKG- PEDV    
NP_742139.1 KYFNTVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYKG- BCoV    
NP_835353.1 IDYNVVTQRMCAIGPDVFLHKCYRCPAEIVNTVSELVYENKFVPVKEASKQCFKIFERG- HCoV-229E
NP_740617.1 RYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKNDNSSMCFKVYYKG- MHV     
NP_740630.1 KDYNVVTNLMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRECFKVIVNNG IBV     
Consensus   p.aNsVTpbMhsl.PDlFL.pCYRCP.EIVcTVS.LVY=NKh.s.p.pSpbCFKhah+G 




NP_828870.1 --VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSS SARS-CoV
NP_840010.1 --QVQIESNSSINNKQLEVVKAFLAHNPKWRKAVFISPYNSQNYVARRLLGLQTQTVDSA TGEV    
NP_839966.1 --NVQVDNGSSINRRQLDVVRMFLAKNPRWSKAVFISPYNSQNYVASRLLGLQIQTVDSS PEDV    
NP_742139.1 --VTTHESSSAVNMQQIYLINKFLKANPLWHKAVFISPYNSQNFAAKRVLGLQTQTVDSA BCoV    
NP_835353.1 --SVQVDNGSSINRRQLDVVKRFIHKNSTWSKAVFISPYNSQNYVAARLLGLQTQTVDSA HCoV-229E
NP_740617.1 --QTTHESSSAVNMQQIHLISKFLKANPSWSNAVFISPYNSQNYVAKRVLGLQTQTVDSA MHV     
NP_740630.1 NSDVGHESGSAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLGLNVQTVDSS IBV     
Consensus     .sp.=puSulN.pQl.llp.Fl..Ns.WpcAVFISPYNSQNhlA.RlLGLpsQTVDSu




NP_828870.1 QGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRD-LYDKLQFTSLEIPRR SARS-CoV
NP_840010.1 QGSEYDYVIYTQTSDTQHATNVNRFNVAITRAKVGILCIMCDRT-MYENLDFYELKD--- TGEV    
NP_839966.1 QGSEYDYVIYAQTSDTAHASNVNRFNVAITRAKKGILCIMCDRS-LFDLLKFFELKL--- PEDV    
NP_742139.1 QGSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSNMQ-LFEALQFTTLTLDKV BCoV    
NP_835353.1 QGSEYDYVIFAQTSDTAHACNANRFNVAITRAKKGIFCIMSDRT-LFDALKFFEITM--- HCoV-229E
NP_740617.1 QGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSSMQ-LFESLNFTTLTLDKI MHV     
NP_740630.1 QGSEYDYVIFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALKFTELDS--- IBV     
Consensus   QGSEYDYVIasQTu=T.HusNlNRFNVAITRAKbGILClMopbp La=.LpF.pLp.   




NP_828870.1 N---VATLQ SARS-CoV
NP_840010.1 ---SKIGLQ TGEV    
NP_839966.1 -----SDLQ PEDV    
NP_742139.1 PQAVETRVQ BCoV    
NP_835353.1 -----TDLQ HCoV-229E
NP_740617.1 N---NPRLQ MHV     
NP_740630.1 ----ETSLQ IBV     
Consensus        spLQ                                                  

Similarities are highlighted by colors, if at least 80% of residues in a column are identical or fall into at least one of the following amino acid groups: aromatic (FHWY), aliphatic (ILVA), hydrophobic (ACFILMVWY), alcohol (STC), charged (DEHKR), positive (HKR), negative (DE), polar (CDEHKNQRST), tiny (AGS), small (ACDGNPSTV), or bulky (EFIKLMQRWY). Mouse-over the accession numbers on the left for full protein names or click for a corresponding sequence record. Abbreviated virus names are shown in italics on the right.

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