NP_828851.1 ---MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRG------------------ SARS-CoV
NP_598310.1 MRSLIYFWLLLPVLPTLSLPQDVTRCQSTTNFRRFFSKFN------VQAPAVVVLGGYLP PEDV
NP_058424.1 MKKLFVVLVVMPLIYGDNFPCSKLTNRTIGNQWNLIETFLLNYSSRLPPNSDVVLGDYFP TGEV
NP_150077.1 --MFLILLISLPTAFAVIGDLKCTTVS-INDVDTGVPSIS-------------------- BCoV
NP_073551.1 ---MFVLLVAYALLH--------------------------------------------- HCoV-229E
NP_045300.1 --MLFVFILFLPSCLGYIGDFRCIQLVNSNGANVSAPSIS-------------------- MHV
NP_040831.1 --MLVTPLLLVTLLCALCSAVLYDSSS--------------------------------- IBV
Consensus hhhhllhhs.h.s...s.......
NP_828851.1 ---VYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHTFG--------------NPVIP SARS-CoV
NP_598310.1 SMNSSSWYCGTGIETASGVHGIFLSYIDSGQGFEIGISQEP-----FDPSGYQLYLHKAT PEDV
NP_058424.1 TVQPWFNCIRNDSNDLYVTLENLKALYWDYATENITWNHRQRLNVVVNGYPYSITVTTTR TGEV
NP_150077.1 ------------TDTVDVTNGLGTYYVLDRVYLNTTLLLNG--------------YYPTS BCoV
NP_073551.1 ------------------------------------------------------------ HCoV-229E
NP_045300.1 ------------TETVEVSQGLGTYYVLDRVYLNATLLLTG--------------YYPVD MHV
NP_040831.1 ----------------------YVYYYQSAFRPPSGWHLQG------------------- IBV
Consensus ...hh.p............
NP_828851.1 FKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVS- SARS-CoV
NP_598310.1 NGNTNAIARLRICQFPDNKTLGPTVNDVTTGRNCLFNKAIPAYMRDGKDIVVGITWD--- PEDV
NP_058424.1 NFNSAEGAIICICKGSPPTTTTESSLTCNWGSECRLNHKFPICPSNSEANCGNMLYGLQW TGEV
NP_150077.1 GSTYRNMALKGTLLLSTLWFKPPFLSDFTNGIFAKVKNTKVIKDGVMYSEFPAITIG--- BCoV
NP_073551.1 ---------IAGCQTTN-----------------GLNTSYSVCNG--------------- HCoV-229E
NP_045300.1 GSKFRNLALTGTNSVSLSWFQPPYLSQFNDGIFAKVQNLKTSTPSGATAYFPTIVIG--- MHV
NP_040831.1 -------GAYAVVNISSEFNNAGSSSGCTVGIIHGGRVVNASSIAMTAP----------- IBV
Consensus u....sp.s.....s......p.u.....pp..s...u....
NP_828851.1 ---------------KPMGTQTHTMIFDNAFN--------------------------CT SARS-CoV
NP_598310.1 --NDRVTVFADKIYHFYLKNDWSRVATRCYNRRSCAMQYVYTPTYYMLN--------VTS PEDV
NP_058424.1 FADEVVAYLHGASYRISFENQWSGTVTFGDMRATTLEVAGTLVDLWWFNPVYDVSYYRVN TGEV
NP_150077.1 ---------------STFVNTSYSVVVQPHTTILGNKLQGFLEISVCQYTMCEYPNTICN BCoV
NP_073551.1 ------------------------------------------------------------ HCoV-229E
NP_045300.1 ---------------SLFGYTSYTVVIEPYN--------GVIMASVCQYTICLLPYTDCK MHV
NP_040831.1 ------------------------------------------------------------ IBV
Consensus
NP_828851.1 FEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIF SARS-CoV
NP_598310.1 AGEDGIYYEPCTANCTGYAANVFATDSNGHIPEGFSFNNWFLLSNDSTLLHGKVVSNQPL PEDV
NP_058424.1 NKNGTTVVSNCTDQCASYVANVFTTQPGGFIPSDFSFNNWFLLTNSSTLVSGKLVTKQPL TGEV
NP_150077.1 PN-LGNQRVELWHWDTGVVSCLYKRNFTYDVNADYLYFHFYQEGGTFYAYFTDTGVVTKF BCoV
NP_073551.1 --------------CVGYSENVFAVESGGYIPSDFAFNNWFLLTNTSSVVDGVVRSFQPL HCoV-229E
NP_045300.1 PNTNGNKLIGFWHTDVKPPICVLKRNFTLNVNADAFYFHFYQHGGTFYAYYADKPSATTF MHV
NP_040831.1 ------------SSGMAWSSSQFCTAHCNFSDTTVFVTHCYKHGG--CPLTGMLQQNLIR IBV
Consensus ..psu.s.plh....s...s.sh.a.paab.sss..lh.u.......h
NP_828851.1 KLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQ SARS-CoV
NP_598310.1 LVNCLLAIPKIYGLGQFFSFNHTMDGVCNGAAVDRAPEALRFNINDTSVILAEG--SIVL PEDV
NP_058424.1 LVNCLWPVPSFEEAASTFCFEGAGFDQCNGAVLNNTVDVIRFNLNFTTNVQSGKGATVFS TGEV
NP_150077.1 LFNVYLGTVLSHYYVMPLTCN----SALTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKS BCoV
NP_073551.1 LLNCLWSVSGLRFTTGFVYFNGTGRGDCKGFSSDVLSDVIRYNLNFEENLRRG---TILF HCoV-229E
NP_045300.1 LFSVYIGDILTQYYVLPFICNPTAGSTFAPRYWVTPLVKRQYLFNFNQKGVITSAVDCAS MHV
NP_040831.1 VSAMKNGQLFYNLTVSVAKYPTFRSFQCVNNLTSVYLNGDLVYTSNETIDVTSAGVYFKA IBV
Consensus lhshbhs....p..s..h.hs....s.hss.h.ss..ps.pa.hp.pp...... ph..
NP_828851.1 NPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVR-FPNITNLCPFGEVFNATKFPSVYA SARS-CoV
NP_598310.1 HTALG---TNLSFVCSNSSDPHLAIFAIPLGATEVPYYCFLKVDTYNSTVYKFLAVLPPT PEDV
NP_058424.1 LNTTGGVTLEISCYTVSDS-SFFSYGEIPFGVTDGPRYCYVHY---NGTALKYLGTLPPS TGEV
NP_150077.1 DFMSEIKCKTLSIAPSTGVYELNGYTVQPIADVYRRIPNLPDCN-IEAWLNDKSVPSPLN BCoV
NP_073551.1 KTSYG----VVVFYCTNNT-LVSGDAHIPFGTVLGNFYCFVNTTIGNETTSAFVGALPKT HCoV-229E
NP_045300.1 SYTSEIKCKTQSMLPSTGVYELSGYTVQPVGVVYRRVANLPACN-IEEWLTARSVPSPLN MHV
NP_040831.1 GGPITYKVMREVKALAYFVNGTAQDVILCDGSPRGLLACQYNTGNFSDGFYPFTNSSLVK IBV
Consensus ..... ..bshh.spss ...s...bP.Gss...h.ph.p.s .p..h..b.ss.s.p
NP_828851.1 WERKKISNCVADYSVLYNSTFFSTFKCYGVSAT----KLNDLCFSNVYADSFVVKGDDVR SARS-CoV
NP_598310.1 VREIVITKYGDVYVNGFGYLHLGLLDAVTINFTGHGTDDDVSGFWTIASTNFVDALIEVQ PEDV
NP_058424.1 VKEIAISKWGHFYINGYNFFSTFPIDCISFNLT----TGDSDVFWTIAYTSYTEALVQVE TGEV
NP_150077.1 WERKTFSNCNFNMSSLMSFIQAYSFTCNNIDAA----KIYGMCFSSITIDKFAIPNGRKV BCoV
NP_073551.1 VREFVISRTGHFYINGYRYFTLGNVEAVNFNVT----TAETTDFCTVALASYADVLVNVS HCoV-229E
NP_045300.1 WERKTFQNCNFNLSSLLRYVQAESLFCNNIDAS----KVYGRCFGSISVDKFAVPRSRQV MHV
NP_040831.1 QKFIVYRENSVNTTCTLHNFIFHNETGANPNPS--GVQNIQTYQTKTAQSGYYNFNFSFL IBV
Consensus hccbshpp.s..h.p.hp.h.h.shph.phpho p..s.sF.pls.ppah....p..
NP_828851.1 QIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDAT------STGNYNYKYRYLRHGKLR SARS-CoV
NP_598310.1 GTSIQRILYCDDPVSQLKCSQVAFDLDDGFYPISSRNLLSHEQPISFVTLPSFNDHSFVN PEDV
NP_058424.1 NTAITKVTYCNSHVNNIKCSQITANLNNGFYPVSS--SEVGLVNKSVVLLPSFYTHTIVN TGEV
NP_150077.1 DLQLGNLGYLQSFNYRIDTTATSCQLYYNLPAANVS--VSRFNPSTWNRRFGFTEQSVFK BCoV
NP_073551.1 QTSIANIIYCNSVINRLRCDQLSFDVPDGFYSTSP--IQSVELPVSIVSLPVYHKHTFIV HCoV-229E
NP_045300.1 DLQLGNSGFLQTANYKIDTAATSCQLHYTLPKNNVT--INNHNPSSWNRRYGFNDAGVFG MHV
NP_040831.1 SSFVYKESNFMYGSYHPSCKFRLETINNGLWFNSLS------VSIAYGPLQGGCKQSVFK IBV
Consensus p..l.p..hh.p.s.plpop..shpl..sh...ps .s.phs.b.sa.cpshh.
NP_828851.1 PFER-------------------------------------------------------- SARS-CoV
NP_598310.1 ITVS-----AAFGGLSSANLVASDTTINGFSS-------FCVDTRQFTITLFYNVTNSYG PEDV
NP_058424.1 ITIGLGMKRSGYGQPIASTLS--NITLPMQDHN---TDVYCIRSDQFS-VYVHSTCKSAL TGEV
NP_150077.1 PQPAGVFTDHDVVYAQHCFKASTNFCPCKLDGSLCVGNGPGIDAGYKTSGIGTCPAGTNY BCoV
NP_073551.1 LYVDFKPQ-SGGGKCFNCYPAGVNITLANFNET---KGPLCVDTSHFTTKYVAVYANVGR HCoV-229E
NP_045300.1 KN------QHDVVYAQQCFTVRSSYCPC-------------------------------- MHV
NP_040831.1 GRAT-------------------------------------------------------- IBV
Consensus ....
NP_828851.1 ------------------------------DISNVPFSPDGKPCTPPALNCYWPLNDYGF SARS-CoV
NP_598310.1 YVS--------------KSQDSNCPFTLQSVNDYLSFSKFCVSTSLLAGACTIDLFGYPA PEDV
NP_058424.1 WDNIFKRNCTDVLDATAVIKTGTCPFSFDKLNNYLTFNKFCLSLSPVGANCKFDVAA-RT TGEV
NP_150077.1 LTCHNAAQCDCLCTPDPITSKATGPYKCPQTKYLVGIGEHCSGLAIKSDHCG----GNPC BCoV
NP_073551.1 WS--------------ASINTGNCPFSFGKVNNFVKFGSVCFSLKDIPGGCAMPIVANWA HCoV-229E
NP_045300.1 ------------AQPDIVSPCTT---QTKPKSAFVNVGDHCEGLGVLEDNCGNADPHKGC MHV
NP_040831.1 ------------------------------CCYAYSYGGPSLCKGVYSGELDHNFECGLL IBV
Consensus .p.hlshu..o.s.s..ss.C..s..s..h
NP_828851.1 YTTTGIGY-------------QPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFN SARS-CoV
NP_598310.1 FGSGVKLT-------------SLYFQFTKGELITGTPKPLEGITDVSFMTLDVCTKYTIY PEDV
NP_058424.1 RTNEQVVR-------------SLYVIYEEGDNIVGVPSDNSGVHDLSVLHLDSCTDYNIY TGEV
NP_150077.1 TCQPQAFLGWSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGVCVNYDLY BCoV
NP_073551.1 YSKYYTIG-------------SLYVSWSDGDGITGVPQPVEGVSSFMNVTLDKCTKYNIY HCoV-229E
NP_045300.1 ICANNSFIGWSHDTCLVNDRCQIFANILLNGINSGTTCSTDLQLPNTEVVTGICVKYDLY MHV
NP_040831.1 VYVTKSGG---------------------SRIQTATEPPVITQNNYNNITLNTCVDYNIY IBV
Consensus .s...... p.a..h..s...suss.ssp..ps.p.l.bs.CspYplY
NP_828851.1 GLTGTGVLTPSSKRFQP--------FQQFGRDVSDFTDSVRDPKTSEILDISPCAFGGVS SARS-CoV
NP_598310.1 GFKGEGIITLTNSSILA---------GVYYTSDSGQLLAFKNVTSGAVYSVTPCSFSEQA PEDV
NP_058424.1 GRTGVGIIRQTNRTLLS---------GLYYTSLSGDLLGFKNVSDGVIYSVTPCDVSAQA TGEV
NP_150077.1 GITGQGIFVEVNATYYNS-------WQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVS BCoV
NP_073551.1 DVSGVGVIRVSNDTFLN---------GITYTSTSGNLLGFKDVTKGTIYSITPCNPPDQL HCoV-229E
NP_045300.1 GITGQGVFKEVKADYYNS-------WQTLLYDVNGNLNGFRDLTTNKTYTIRSCYSGRVS MHV
NP_040831.1 GRTGQGFITNVTDSAVSYNYLADAGLAILDTSGSIDIFVVQGEYGLNYYKVNPCEDVNQQ IBV
Consensus GboG.Glhp.sp.phhs ..h..pspspl.uh+p..ps..aplpsC..s...
NP_828851.1 VITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHV SARS-CoV
NP_598310.1 AYVNDD--IVGVISSLSNS--TFNNTRELPGFFYHSNDGSN--------------CTEPV PEDV
NP_058424.1 AVIDGT--IVGAITSINSELLGLTHWTTTPNFYYYSIYNYTNDRTRGTAIDSNDVDCEPV TGEV
NP_150077.1 AAFHAN--SSEPALLFRNIKCNYVFNNTLSRQLQPINYFDSYLGCVVNADNSTSSVVQTC BCoV
NP_073551.1 VVYQQA--VVGAMLSENFTSYGFSNVVELPKFFYASNGTYN--------------CTDAV HCoV-229E
NP_045300.1 AAFHKD--APEPALLYRNINCSYVFSNNISREENPLNYFDSYLGCVVNADNRTDEALPNC MHV
NP_040831.1 FVVSGGK-LVGILTSRNETGSQLLENQFYIKITNGTRRFRRSITEN--------VANCPY IBV
Consensus llhp.s .s.sl..bpp...shs.s...spbb.......p sspsh
NP_828851.1 DTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSI SARS-CoV
NP_598310.1 LVYSNIGVCKSGS-------IGYVPSQYGQVK-IAPTVTGN----------ISIPTNFSM PEDV
NP_058424.1 ITYS
