Severe Acute Respiratory Syndrome (SARS)

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Pre-computed multiple alignment of the coronavirus E proteins 
NP_828854.1 -----MYSFVSEETGTLIVNSVLLFLAF-VVFLLVTLAILTALRLCAYCCNIVNVSLVKP SARS-CoV
NP_598312.1 -----MLQLVNDNG--LVVNVILWLFVL-FFLLIISITFVQLVNLCFTCHRLCNSAVYTP PEDV    
NP_058426.1 MTFPRALTVIDDNG--MVINIIFWFLLI-IILILLSIALLNIIKLCMVCCNLGRTVIIVP TGEV    
NP_150081.1 --MFMADAYFADTV--WYVGQIIFIVAICLLVIIVVVAFLATFKLCIQLCGMCNTLVLSP BCoV    
NP_073554.1 ----MFLKLVDDHA--LVVNVLLWCVVL-IVILLVCITIIKLIKLCFTCHMFCNRTVYGP HCoV-229E
NP_068673.1 ----MFNLFLTDTV--WYVGQIIFIFAVCLMVTIIVVAFLASIKLCIQLCGLCNTLVLSP MHV     
NP_040834.1 --MNLLNKSLEENG--SFLTALYIIVGF-LALYLLGRALQAFVQAADACCLFWYTWVVIP IBV     
Consensus        h..hlp=ps  hhls.lhhhhlh lhlhllslshl..lpLCh.hp.hhpp.lh.P


NP_828854.1 ----TVYVYS----RVKNLN-SSEGVPDLLV------------------------- SARS-CoV
NP_598312.1 ----IGRLYR----VYKSYM-RIDPLPSTVIDV----------------------- PEDV    
NP_058426.1 ----AQHAYD----AYKNFM-RIKAYNPDGALLA---------------------- TGEV    
NP_150081.1 ----SIYVFNRGRQFYEFYN-DVKPPVLDVDDV----------------------- BCoV    
NP_073554.1 ----IKNVYH----IYQSYM-HIDPFPKRVIDF----------------------- HCoV-229E
NP_068673.1 ----SIYLYDRSKQLYKYYNEEMRLPLLEVDDI----------------------- MHV     
NP_040834.1 GAKGTAFVYK---YTYGRKLNNPELEAVIVNEFPKNGWNNKNPANFQDAQRDKLYS IBV     
Consensus       ...lYp    .Yp.h. p.c..s..l..h

Similarities are highlighted by colors, if at least 80% of residues in a column are identical or fall into at least one of the following amino acid groups: aromatic (FHWY), aliphatic (ILVA), hydrophobic (ACFILMVWY), alcohol (STC), charged (DEHKR), positive (HKR), negative (DE), polar (CDEHKNQRST), tiny (AGS), small (ACDGNPSTV), or bulky (EFIKLMQRWY). Mouse-over the accession numbers on the left for full protein names or click for a corresponding sequence record. Abbreviated virus names are shown in italics on the right.

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