Microarray is a hybridization of a nucleic acid sample (target) to a very large set of oligonucleotide probes, which are attached to a solid support, to determine sequence or to detect variations in a gene sequence or expression or for gene mapping (MeSH).
Several competing technologies for microarray probe implementation have emerged. Affymetrix pioneered this field with by using in situ synthesized oligonucleotides as probes and by designing microarrays in silico, thereby obviating the need for the management of clone libraries.
Two-color microarray principle
» Gene expression Omnibus (GEO) is a data repository of high-throughput gene expressions and hybridization arrays
» References for genetic analysis software including microarray analysis METREX software
» About microarray technology in PubMed
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