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    LOC100142406 3'-5' RNA helicase YTHDC2 [ Tribolium castaneum (red flour beetle) ]

    Gene ID: 100142406, updated on 12-Apr-2024

    Summary

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    Gene symbol
    LOC100142406
    Gene description
    3'-5' RNA helicase YTHDC2
    Locus tag
    TcasGA2_TC011100
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tribolium castaneum
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium
    Also known as
    bgcn
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_04 current icTriCast1.1 (GCF_031307605.1) 7 NC_087400.1 (3698494..3710212)
    103 previous assembly Tcas5.2 (GCF_000002335.3) Unplaced Scaffold NW_015450233.1 (394038..405726, complement)

    Chromosome 7 - NC_087400.1Genomic Context describing neighboring genes Neighboring gene Seryl-tRNA synthetase, mitochondrial Neighboring gene venom carboxylesterase-6 Neighboring gene cuticular protein analogous to peritrophins 1-J Neighboring gene Cadherin 99C Neighboring gene uncharacterized LOC107398838

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BeetleBase in 2010: revisions to provide comprehensive genomic information for Tribolium castaneum. Kim HS, et al. Nucleic Acids Res, 2010 Jan. PMID 19820115, Free PMC Article
    2. The genome of the model beetle and pest Tribolium castaneum. Tribolium Genome Sequencing Consortium, et al. Nature, 2008 Apr 24. PMID 18362917

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3'-5' RNA helicase YTHDC2
    Names
    AUGUSTUS-3.0.2_11100
    GLEAN_11100
    benign gonial cell neoplasm
    probable ATP-dependent RNA helicase YTHDC2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_031307605.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference icTriCast1.1 Primary Assembly

    Genomic

    1. NC_087400.1 Reference icTriCast1.1 Primary Assembly

      Range
      3698494..3710212
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008200536.3 → XP_008198758.1  3'-5' RNA helicase YTHDC2 isoform X2

      Conserved Domains (10) summary
      cd02325
      Location:20 → 79
      R3H; R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich ...
      smart00847
      Location:695 → 780
      HA2; Helicase associated domain (HA2) Add an annotation
      COG1643
      Location:145 → 1004
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd00046
      Location:171 → 312
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00204
      Location:391 → 462
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00271
      Location:494 → 622
      Helicase_C; Helicase conserved C-terminal domain
      pfam04146
      Location:1044 → 1161
      YTH; YT521-B-like domain
      pfam07717
      Location:817 → 923
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
      pfam13857
      Location:396 → 450
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:409 → 440
      ANK; ANK repeat [structural motif]

    2. XM_008200535.3 → XP_008198757.1  3'-5' RNA helicase YTHDC2 isoform X1

      See identical proteins and their annotated locations for XP_008198757.1

      UniProtKB/TrEMBL
      D6X4B1
      Conserved Domains (10) summary
      cd02325
      Location:30 → 89
      R3H; R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich ...
      smart00847
      Location:705 → 790
      HA2; Helicase associated domain (HA2) Add an annotation
      COG1643
      Location:155 → 1014
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd00046
      Location:181 → 322
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00204
      Location:401 → 472
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00271
      Location:504 → 632
      Helicase_C; Helicase conserved C-terminal domain
      pfam04146
      Location:1054 → 1171
      YTH; YT521-B-like domain
      pfam07717
      Location:827 → 933
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
      pfam13857
      Location:406 → 460
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:419 → 450
      ANK; ANK repeat [structural motif]
    Nucleotide Protein Strain
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