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    STE4 G protein subunit beta [ Saccharomyces cerevisiae S288c ]

    Gene ID: 854387, updated on 7-Feb-2016
    Gene symbol
    STE4
    Gene description
    G protein subunit beta
    Primary source
    SGD:S000005738
    Locus tag
    YOR212W
    Gene type
    protein coding
    RNA name
    G protein subunit beta
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    HMD2
    See STE4 in MapViewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (742910..744181)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase core subunit RPB10 Neighboring gene dynamin-related GTPase MGM1 Neighboring gene Sas5p Neighboring gene Spr2p

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • MAPK Signaling Pathway, organism-specific biosystem (from WikiPathways)
      MAPK Signaling Pathway, organism-specific biosystemThe MAPK/ERK pathway is a signal transduction pathway that couples intracellular responses to the binding of growth factors to cell surface receptors. In many cell types, activation of this pathway p...
    • MAPK signaling pathway - yeast, organism-specific biosystem (from KEGG)
      MAPK signaling pathway - yeast, organism-specific biosystemThe S. cerevisiae genome encodes multiple MAP kinase orthologs. One (Fus3) mediates cellular response to peptide pheromones. Another (Kss1) permits adjustment to nutrient limiting conditions. A third...
    • MAPK signaling pathway - yeast, conserved biosystem (from KEGG)
      MAPK signaling pathway - yeast, conserved biosystemThe S. cerevisiae genome encodes multiple MAP kinase orthologs. One (Fus3) mediates cellular response to peptide pheromones. Another (Kss1) permits adjustment to nutrient limiting conditions. A third...
    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    signal transducer activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    heterotrimeric G-protein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heterotrimeric G-protein complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mating projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    G protein subunit beta
    NP_014855.3
    • G protein beta subunit; forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      742910..744181
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183631.3NP_014855.3  G protein subunit beta [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_014855.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P18851
      Conserved Domains (2) summary
      COG2319
      Location:91420
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:87419
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...