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    Cstb cystatin B [ Mus musculus (house mouse) ]

    Gene ID: 13014, updated on 15-Nov-2015
    Official Symbol
    Cstbprovided by MGI
    Official Full Name
    cystatin Bprovided by MGI
    Primary source
    MGI:MGI:109514
    See related
    Ensembl:ENSMUSG00000005054
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Stfb; AA960480
    Orthologs
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (78425670..78427622)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (77888415..77890367)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene LSM7 homolog, U6 small nuclear RNA associated pseudogene Neighboring gene ribosomal RNA processing 1 homolog (S. cerevisiae) Neighboring gene microRNA 6907 Neighboring gene microRNA 6410 Neighboring gene pyridoxal (pyridoxine, vitamin B6) kinase Neighboring gene microRNA 6908

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cysteine-type endopeptidase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    endopeptidase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    peptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    poly(A) RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protease binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    adult locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of endopeptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of peptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of proteolysis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular IEA
    Inferred from Electronic Annotation
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007793.3NP_031819.1  cystatin-B

      See identical proteins and their annotated locations for NP_031819.1

      Status: VALIDATED

      Source sequence(s)
      BC056170, BY091749
      Consensus CDS
      CCDS23964.1
      UniProtKB/Swiss-Prot
      Q62426
      Related
      ENSMUSP00000005185, ENSMUST00000005185
      Conserved Domains (1) summary
      cd00042
      Location:479
      CY; Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

      Range
      78425670..78427622
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000032.1 Alternate Mm_Celera

      Range
      79447767..79449719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)