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ZNF331 zinc finger protein 331 [ Homo sapiens (human) ]

Gene ID: 55422, updated on 19-Jul-2014
Official Symbol
ZNF331provided by HGNC
Official Full Name
zinc finger protein 331provided by HGNC
Primary source
HGNC:15489
See related
Ensembl:ENSG00000130844; HPRD:05827; MIM:606043; Vega:OTTHUMG00000163019
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RITA; ZNF361; ZNF463
Summary
This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. A pseudogene of this gene is located on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
See ZNF331 in Epigenomics, MapViewer
Location:
19q13.42
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 19 NC_000019.10 (53520923..53580269)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (54024177..54083523)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein L39 pseudogene 37 Neighboring gene vomeronasal 1 receptor 103 pseudogene Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 pseudogene Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • DKFZp686L0787

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
zinc finger protein 331
Names
zinc finger protein 331
zinc finger protein 361
zinc finger protein 463
KRAB zinc finger protein
rearranged in thyroid adenomas
C2H2-like zinc finger protein rearranged in thyroid adenomas

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079906.1NP_001073375.1  zinc finger protein 331

    See proteins identical to NP_001073375.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    AC011487, AF412402, BF057584, CR749560
    Consensus CDS
    CCDS33102.1
    UniProtKB/TrEMBL
    Q68D63
    UniProtKB/TrEMBL
    Q71QC5
    UniProtKB/Swiss-Prot
    Q9NQX6
    Conserved Domains (3) summary
    cd07765
    Location:645
    Blast Score: 218
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:185441
    Blast Score: 122
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:341366
    Blast Score: 92
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001079907.1NP_001073376.1  zinc finger protein 331

    See proteins identical to NP_001073376.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    AC011487, AF412401, CR749560
    Consensus CDS
    CCDS33102.1
    UniProtKB/TrEMBL
    Q68D63
    UniProtKB/TrEMBL
    Q71QC6
    UniProtKB/Swiss-Prot
    Q9NQX6
    Conserved Domains (3) summary
    cd07765
    Location:645
    Blast Score: 218
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:185441
    Blast Score: 122
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:341366
    Blast Score: 92
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001253798.1NP_001240727.1  zinc finger protein 331

    See proteins identical to NP_001240727.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    AC011487, BQ003434, DA060280
    Consensus CDS
    CCDS33102.1
    UniProtKB/Swiss-Prot
    Q9NQX6
    Conserved Domains (3) summary
    cd07765
    Location:645
    Blast Score: 218
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:185441
    Blast Score: 122
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:341366
    Blast Score: 92
    zf-H2C2_2; Zinc-finger double domain
  4. NM_001253799.1NP_001240728.1  zinc finger protein 331

    See proteins identical to NP_001240728.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    AC011487, BQ003434, DA237659
    Consensus CDS
    CCDS33102.1
    UniProtKB/Swiss-Prot
    Q9NQX6
    Conserved Domains (3) summary
    cd07765
    Location:645
    Blast Score: 218
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:185441
    Blast Score: 122
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:341366
    Blast Score: 92
    zf-H2C2_2; Zinc-finger double domain
  5. NM_001253800.1NP_001240729.1  zinc finger protein 331

    See proteins identical to NP_001240729.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    AC011487, AF251515, BQ003434
    Consensus CDS
    CCDS33102.1
    UniProtKB/Swiss-Prot
    Q9NQX6
    Conserved Domains (3) summary
    cd07765
    Location:645
    Blast Score: 218
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:185441
    Blast Score: 122
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:341366
    Blast Score: 92
    zf-H2C2_2; Zinc-finger double domain
  6. NM_001253801.1NP_001240730.1  zinc finger protein 331

    See proteins identical to NP_001240730.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    AC011487, AF272148, BQ003434
    Consensus CDS
    CCDS33102.1
    UniProtKB/Swiss-Prot
    Q9NQX6
    Conserved Domains (3) summary
    cd07765
    Location:645
    Blast Score: 218
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:185441
    Blast Score: 122
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:341366
    Blast Score: 92
    zf-H2C2_2; Zinc-finger double domain
  7. NM_018555.5NP_061025.5  zinc finger protein 331

    See proteins identical to NP_061025.5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All variants encode the same protein.
    Source sequence(s)
    AC011487, AK128736, CR749560, DA123838
    Consensus CDS
    CCDS33102.1
    UniProtKB/TrEMBL
    Q68D63
    UniProtKB/Swiss-Prot
    Q9NQX6
    Related
    ENSP00000253144, OTTHUMP00000223045, ENST00000253144, OTTHUMT00000371366
    Conserved Domains (3) summary
    cd07765
    Location:645
    Blast Score: 218
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:185441
    Blast Score: 122
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:341366
    Blast Score: 92
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000019.10 

    Range
    53520923..53580269
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006723259.1XP_006723322.1  

    See proteins identical to XP_006723322.1

    UniProtKB/Swiss-Prot
    Q9NQX6
    Conserved Domains (3) summary
    cd07765
    Location:645
    Blast Score: 218
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:185441
    Blast Score: 122
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:341366
    Blast Score: 92
    zf-H2C2_2; Zinc-finger double domain
  2. XM_005259040.1XP_005259097.1  

    See proteins identical to XP_005259097.1

    UniProtKB/Swiss-Prot
    Q9NQX6
    Conserved Domains (3) summary
    cd07765
    Location:645
    Blast Score: 218
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:185441
    Blast Score: 122
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:341366
    Blast Score: 92
    zf-H2C2_2; Zinc-finger double domain

Alternate HuRef

Genomic

  1. AC_000151.1 

    Range
    50344398..50403248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018930.2 

    Range
    54026017..54085277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)