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    TSPO2 translocator protein 2 [ Homo sapiens (human) ]

    Gene ID: 222642, updated on 15-Nov-2015
    Official Symbol
    TSPO2provided by HGNC
    Official Full Name
    translocator protein 2provided by HGNC
    Primary source
    HGNC:HGNC:21256
    See related
    Ensembl:ENSG00000112212; HPRD:16569; Vega:OTTHUMG00000014666
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BZRPL1
    Orthologs
    See TSPO2 in Epigenomics, MapViewer
    Location:
    6p21.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    107 current GRCh38.p2 (GCF_000001405.28) 6 NC_000006.12 (41041370..41044337)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (41010237..41012076)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101929555 Neighboring gene unc-5 family C-terminal like Neighboring gene apolipoprotein B mRNA editing enzyme catalytic polypeptide like 2 Neighboring gene O-acyl-ADP-ribose deacylase 1

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Clone Names

    • MGC129806, MGC129807

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    cholesterol binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    translocator protein 2
    Names
    benzodiazapine receptor (peripheral)-like 1
    peripheral-type benzodiazepine receptor-like protein 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001010873.2NP_001010873.1  translocator protein 2

      See identical proteins and their annotated locations for NP_001010873.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI052224, BC137565, BU655765, BU657409
      Consensus CDS
      CCDS34444.1
      UniProtKB/Swiss-Prot
      Q5TGU0
      Related
      ENSP00000362255, OTTHUMP00000016363, ENST00000373161, OTTHUMT00000040493
      Conserved Domains (1) summary
      cl01379
      Location:6154
      TspO_MBR; TspO/MBR family
    2. NM_001159726.1NP_001153198.1  translocator protein 2

      See identical proteins and their annotated locations for NP_001153198.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI052224, BC144710
      Consensus CDS
      CCDS34444.1
      UniProtKB/Swiss-Prot
      Q5TGU0
      Related
      ENSP00000419985, OTTHUMP00000214126, ENST00000470917, OTTHUMT00000353408
      Conserved Domains (1) summary
      cl01379
      Location:6154
      TspO_MBR; TspO/MBR family

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p2 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p2 Primary Assembly

      Range
      41041370..41044337
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011514396.1XP_011512698.1  

      See identical proteins and their annotated locations for XP_011512698.1

      UniProtKB/Swiss-Prot
      Q5TGU0
      Conserved Domains (1) summary
      cl01379
      Location:6154
      TspO_MBR; TspO/MBR family
    2. XM_011514397.1XP_011512699.1  

      See identical proteins and their annotated locations for XP_011512699.1

      UniProtKB/Swiss-Prot
      Q5TGU0
      Conserved Domains (1) summary
      cl01379
      Location:6154
      TspO_MBR; TspO/MBR family

    Alternate CHM1_1.1

    Genomic

    1. NC_018917.2 Alternate CHM1_1.1

      Range
      41012743..41014582
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)