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    SPATA31A5 SPATA31 subfamily A member 5 [ Homo sapiens (human) ]

    Gene ID: 727905, updated on 3-Apr-2024

    Summary

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    Official Symbol
    SPATA31A5provided by HGNC
    Official Full Name
    SPATA31 subfamily A member 5provided by HGNC
    Primary source
    HGNC:HGNC:32005
    See related
    Ensembl:ENSG00000276581 AllianceGenome:HGNC:32005
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM75A5
    Summary
    Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis (RPKM 8.0) See more
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    Genomic context

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    Location:
    9q12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (60914372..60920653)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (41500679..41506925)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene CNTNAP3 pseudogene 4 Neighboring gene uncharacterized LOC105379434 Neighboring gene 6-pyruvoyltetrahydropterin synthase pseudogene Neighboring gene family with sequence similarity 74 member A6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence. Zuo Y, et al. Biochem Biophys Res Commun, 2010 Oct 15. PMID 20850414

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    spermatogenesis-associated protein 31A5
    Names
    family with sequence similarity 75, member A5
    protein FAM75A5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113541.3 → NP_001107013.1  spermatogenesis-associated protein 31A5

      See identical proteins and their annotated locations for NP_001107013.1

      Status: VALIDATED

      Source sequence(s)
      AL590491
      Consensus CDS
      CCDS47970.1
      UniProtKB/Swiss-Prot
      Q5VU36
      UniProtKB/TrEMBL
      B2RUU1
      Related
      ENSP00000485628.1, ENST00000437823.5
      Conserved Domains (2) summary
      pfam14650
      Location:396 → 754
      FAM75; FAM75 family
      pfam15371
      Location:76 → 155
      DUF4599; Domain of unknown function (DUF4599)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      60914372..60920653
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047423839.1 → XP_047279795.1  spermatogenesis-associated protein 31A5 isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5VU36.1 GenPept UniProtKB/Swiss-Prot:Q5VU36

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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