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    FT PEBP (phosphatidylethanolamine-binding protein) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842859, updated on 15-Mar-2024

    Summary

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    Gene symbol
    FT
    Gene description
    PEBP (phosphatidylethanolamine-binding protein) family protein
    Primary source
    Araport:AT1G65480
    Locus tag
    AT1G65480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F5I14.3; F5I14_3; FLOWERING LOCUS T; REDUCED STEM BRANCHING 8; RSB8
    Summary
    FT, together with LFY, promotes flowering and is antagonistic with its homologous gene, TERMINAL FLOWER1 (TFL1). FT is expressed in leaves and is induced by long day treatment. Either the FT mRNA or protein is translocated to the shoot apex where it induces its own expression. Recent data suggests that FT protein acts as a long-range signal. FT is a target of CO and acts upstream of SOC1.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (24331373..24333999)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene HXXXD-type acyl-transferase family protein Neighboring gene chromatin assembly factor-1 (FASCIATA1) (FAS1) Neighboring gene ncRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The FLOWERING LOCUS T gene expression is controlled by high-irradiance response and external coincidence mechanism in long days in Arabidopsis. Lee N, et al. New Phytol, 2023 Jul. PMID 37084001,
    2. FLOWERING LOCUS T mediates photo-thermal timing of inflorescence meristem arrest in Arabidopsis thaliana. González-Suárez P, et al. Plant Physiol, 2023 Jul 3. PMID 36943252, Free PMC Article
    3. Florigen sequestration in cellular membranes modulates temperature-responsive flowering. Susila H, et al. Science, 2021 Sep 3. PMID 34516842
    4. SIN3 LIKE genes mediate long-day induction of flowering but inhibit the floral transition in short days through histone deacetylation in Arabidopsis. Huang F, et al. Plant J, 2019 Oct. PMID 31168864
    5. Targeted DNA methylation represses two enhancers of FLOWERING LOCUS T in Arabidopsis thaliana. Zicola J, et al. Nat Plants, 2019 Mar. PMID 30833712

    See all (125) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A dephosphorylation-dependent molecular switch for FT repression mediates flowering in Arabidopsis.
      Title: A dephosphorylation-dependent molecular switch for FT repression mediates flowering in Arabidopsis.
    2. Low temperature-mediated repression and far-red light-mediated induction determine morning FLOWERING LOCUS T expression levels.
      Title: Low temperature-mediated repression and far-red light-mediated induction determine morning FLOWERING LOCUS T expression levels.
    3. Interaction of a bacterial non-classically secreted RNase H with a citrus B-Box zinc finger protein delays flowering in Arabidopsis thaliana and suppresses the expression of FLOWERING LOCUS T.
      Title: Interaction of a bacterial non-classically secreted RNase HⅠ with a citrus B-Box zinc finger protein delays flowering in Arabidopsis thaliana and suppresses the expression of FLOWERING LOCUS T.
    4. Photoperiodic flowering in Arabidopsis: Multilayered regulatory mechanisms of CONSTANS and the florigen FLOWERING LOCUS T.
      Title: Photoperiodic flowering in Arabidopsis: Multilayered regulatory mechanisms of CONSTANS and the florigen FLOWERING LOCUS T.
    5. FLOWERING LOCUS T mediates photo-thermal timing of inflorescence meristem arrest in Arabidopsis thaliana.
      Title: FLOWERING LOCUS T mediates photo-thermal timing of inflorescence meristem arrest in Arabidopsis thaliana.
    6. The FLOWERING LOCUS T gene expression is controlled by high-irradiance response and external coincidence mechanism in long days in Arabidopsis.
      Title: The FLOWERING LOCUS T gene expression is controlled by high-irradiance response and external coincidence mechanism in long days in Arabidopsis.
    7. The bZIP transcription factor AREB3 mediates FT signalling and floral transition at the Arabidopsis shoot apical meristem.
      Title: The bZIP transcription factor AREB3 mediates FT signalling and floral transition at the Arabidopsis shoot apical meristem.
    8. ERF1 delays flowering through direct inhibition of FLOWERING LOCUS T expression in Arabidopsis.
      Title: ERF1 delays flowering through direct inhibition of FLOWERING LOCUS T expression in Arabidopsis.
    9. Ectopic expression of the Arabidopsis florigen gene FLOWERING LOCUS T in seeds enhances seed dormancy via the GA and DOG1 pathways.
      Title: Ectopic expression of the Arabidopsis florigen gene FLOWERING LOCUS T in seeds enhances seed dormancy via the GA and DOG1 pathways.
    10. Florigen sequestration in cellular membranes modulates temperature-responsive flowering.
      Title: Florigen sequestration in cellular membranes modulates temperature-responsive flowering.
    Submit: New GeneRIF Correction See all GeneRIFs (113)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_105222.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatidylethanolamine binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within meristem determinacy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within photoperiodism, flowering IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of flower development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of stomatal movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PEBP (phosphatidylethanolamine-binding protein) family protein
    NP_176726.1
    • FLOWERING LOCUS T (FT); FUNCTIONS IN: phosphatidylethanolamine binding, protein binding; INVOLVED IN: photoperiodism, flowering, positive regulation of flower development, regulation of flower development; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylethanolamine-binding, conserved site (InterPro:IPR001858), Phosphatidylethanolamine-binding protein PEBP (InterPro:IPR008914); BEST Arabidopsis thaliana protein match is: PEBP (phosphatidylethanolamine-binding protein) family protein (TAIR:AT4G20370.1); Has 2182 Blast hits to 2182 proteins in 306 species: Archae - 0; Bacteria - 0; Metazoa - 594; Fungi - 140; Plants - 1404; Viruses - 3; Other Eukaryotes - 41 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24331373..24333999
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001334207.1 → NP_001320342.1  PEBP (phosphatidylethanolamine-binding protein) family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AMK0

    2. NM_105222.3 → NP_176726.1  PEBP (phosphatidylethanolamine-binding protein) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176726.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04467, Q9SXZ2
      UniProtKB/TrEMBL
      A0A178WM09, A0A5S9WPT9
      Conserved Domains (1) summary
      PLN00169
      Location:1 → 175
      PLN00169; CETS family protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SXZ2.2

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