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    Mir281 microRNA mir-281 [ Apis mellifera (honey bee) ]

    Gene ID: 732503, updated on 22-Apr-2023

    Summary

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    Gene symbol
    Mir281
    Gene description
    microRNA mir-281
    See related
    miRBase:MI0001587
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Apis mellifera
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea; Anthophila; Apidae; Apis
    Also known as
    Mirn281
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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    Genomic context

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    Location:
    chromosome: LG1
    Exon count:
    1
    Annotation release Status Assembly LG Location
    104 current Amel_HAv3.1 (GCF_003254395.2) LG1 NC_037638.1 (20557512..20557614, complement)
    103 previous assembly Amel_4.5 (GCF_000002195.4) LG1 NC_007070.3 (22275351..22275453, complement)

    Linkage Group LG1 - NC_037638.1Genomic Context describing neighboring genes Neighboring gene isocitrate dehydrogenase [NAD] subunit beta, mitochondrial Neighboring gene vesicle transport protein SEC20 Neighboring gene phosphoinositide 3-kinase regulatory subunit 4 Neighboring gene uncharacterized LOC113218663 Neighboring gene coiled-coil domain containing 13-like Neighboring gene glutamic acid-rich protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MicroRNA signatures characterizing caste-independent ovarian activity in queen and worker honeybees (Apis mellifera L.). Macedo LM, et al. Insect Mol Biol, 2016 Jun. PMID 26853694
    2. Behavioral plasticity in honey bees is associated with differences in brain microRNA transcriptome. Greenberg JK, et al. Genes Brain Behav, 2012 Aug. PMID 22409512, Free PMC Article
    3. ProtoBee: hierarchical classification and annotation of the honey bee proteome. Kaplan N, et al. Genome Res, 2006 Nov. PMID 17065614, Free PMC Article
    4. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Other Names

    • ame-mir-281
    • microRNA 281

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_031520.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      QIUM02000008

    RefSeqs of Annotated Genomes: Apis mellifera Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Amel_HAv3.1 Primary Assembly

    Genomic

    1. NC_037638.1 Reference Amel_HAv3.1 Primary Assembly

      Range
      20557512..20557614 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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