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    Acbd6 acyl-Coenzyme A binding domain containing 6 [ Mus musculus (house mouse) ]

    Gene ID: 72482, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Acbd6provided by MGI
    Official Full Name
    acyl-Coenzyme A binding domain containing 6provided by MGI
    Primary source
    MGI:MGI:1919732
    See related
    Ensembl:ENSMUSG00000033701 AllianceGenome:MGI:1919732
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610010G04Rik; 2610100E10Rik
    Summary
    Predicted to enable fatty-acyl-CoA binding activity and lipid binding activity. Predicted to be located in cytoplasm. Orthologous to human ACBD6 (acyl-CoA binding domain containing 6). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 57.6), ovary adult (RPKM 37.3) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    1 G3; 1 66.92 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (155433845..155564120)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (155558099..155687474)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_02725 Neighboring gene predicted gene, 31772 Neighboring gene predicted gene 5532 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:157405138-157405321 Neighboring gene STARR-positive B cell enhancer ABC_E9484 Neighboring gene STARR-positive B cell enhancer mm9_chr1:157423836-157424136 Neighboring gene STARR-seq mESC enhancer starr_02727 Neighboring gene LIM homeobox protein 4 Neighboring gene STARR-positive B cell enhancer mm9_chr1:157659814-157660115 Neighboring gene quiescin Q6 sulfhydryl oxidase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC106946, MGC144461, MGC144462

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables fatty-acyl-CoA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    acyl-CoA-binding domain-containing protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145781.1 → NP_001139253.1  acyl-CoA-binding domain-containing protein 6 isoform 2

      See identical proteins and their annotated locations for NP_001139253.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK082937, AK165836
      Consensus CDS
      CCDS48398.1
      UniProtKB/Swiss-Prot
      Q9D061
      Related
      ENSMUSP00000095136.4, ENSMUST00000097529.5
      Conserved Domains (1) summary
      pfam00887
      Location:44 → 123
      ACBP; Acyl CoA binding protein

    2. NM_026683.1 → NP_080959.1  acyl-CoA-binding domain-containing protein 6 isoform 3

      See identical proteins and their annotated locations for NP_080959.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK002470, AK082937
      Consensus CDS
      CCDS48397.1
      UniProtKB/Swiss-Prot
      Q9D061
      Related
      ENSMUSP00000079035.7, ENSMUST00000080138.13
      Conserved Domains (1) summary
      pfam00887
      Location:44 → 123
      ACBP; Acyl CoA binding protein

    3. NM_028250.3 → NP_082526.2  acyl-CoA-binding domain-containing protein 6 isoform 1

      See identical proteins and their annotated locations for NP_082526.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AA260937, AK082937, BC115580
      Consensus CDS
      CCDS15385.1
      UniProtKB/Swiss-Prot
      Q3TMN7, Q9D061, Q9DCU4
      UniProtKB/TrEMBL
      Q14BV7
      Related
      ENSMUSP00000049124.4, ENSMUST00000035560.9
      Conserved Domains (4) summary
      cd00204
      Location:165 → 261
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00887
      Location:44 → 123
      ACBP; Acyl CoA binding protein
      pfam12796
      Location:166 → 255
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:191 → 222
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      155433845..155564120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529883.5 → XP_006529946.1  acyl-CoA-binding domain-containing protein 6 isoform X1

      Conserved Domains (2) summary
      sd00045
      Location:98 → 129
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:73 → 162
      Ank_2; Ankyrin repeats (3 copies)

    RNA

    1. XR_387197.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D061.2 GenPept UniProtKB/Swiss-Prot:Q9D061

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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