Lipt2 lipoyl(octanoyl) transferase 2 (putative) [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Lipt2provided by MGI
Official Full Name: lipoyl(octanoyl) transferase 2 (putative)provided by MGI
Primary source: MGI:MGI:1914414
See related: Ensembl:ENSMUSG00000030725 AllianceGenome:MGI:1914414
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2610209A20Rik
Summary: Predicted to enable ligase activity; lipoyl(octanoyl) transferase activity; and octanoyl transferase activity (acting on glycine-cleavage complex H protein). Predicted to be involved in positive regulation of oxygen metabolic process and protein lipoylation. Located in mitochondrion. Orthologous to human LIPT2 (lipoyl(octanoyl) transferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in ovary adult (RPKM 29.8), colon adult (RPKM 15.1) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 E2; 7 54.33 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (99808484..99810138)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (100159277..100160931)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables lipoyl(octanoyl) transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables lipoyl(octanoyl) transferase activity	IDA Inferred from Direct Assay more info	PubMed
enables octanoyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of oxygen metabolic process	ISO Inferred from Sequence Orthology more info
involved_in protein lipoylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein lipoylation	ISO Inferred from Sequence Orthology more info
involved_in protein modification process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial

Names: lipoate-protein ligase B; lipoyl/octanoyl transferase; lipoyltransferase 2; octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase; putative lipoyltransferase 2, mitochondrial; putative octanoyltransferase, mitochondrial

NP_080286.2

EC 2.3.1.181

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.