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    POU2F1 POU class 2 homeobox 1 [ Bos taurus (cattle) ]

    Gene ID: 512840, updated on 3-Apr-2024

    Summary

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    Official Symbol
    POU2F1provided by VGNC
    Official Full Name
    POU class 2 homeobox 1provided by VGNC
    Primary source
    VGNC:VGNC:33174
    See related
    Ensembl:ENSBTAG00000024534
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (1269627..1482009, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene cellular repressor of E1A stimulated genes 1 Neighboring gene CD247 molecule Neighboring gene large ribosomal subunit protein uL11-like Neighboring gene dynactin subunit 5-like Neighboring gene serine/threonine/tyrosine interacting like 2 Neighboring gene glycoprotein A33

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The role of oct-1 in the regulation of tracheal antimicrobial peptide (TAP) and lingual antimicrobial peptide (LAP) expression in bovine mammary epithelial cells. Yang J, et al. Immunogenetics, 2011 Nov. PMID 21674298
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The results from this study clearly demonstrate the involvement of octamer transcription factor-1 in the regulation of tracheal antimicrobial peptide and lingual antimicrobial peptide expression.
      Title: The role of oct-1 in the regulation of tracheal antimicrobial peptide (TAP) and lingual antimicrobial peptide (LAP) expression in bovine mammary epithelial cells.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC142534

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    POU domain, class 2, transcription factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075582.2 → NP_001069050.1  POU domain, class 2, transcription factor 1

      See identical proteins and their annotated locations for NP_001069050.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120288
      UniProtKB/TrEMBL
      A0A3Q1M3H3, Q0VC94
      Related
      ENSBTAP00000034020.3, ENSBTAT00000034119.4
      Conserved Domains (2) summary
      smart00352
      Location:292 → 366
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:396 → 449
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      1269627..1482009 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024987873.2 → XP_024843641.2  POU domain, class 2, transcription factor 1 isoform X3

    2. XM_015461140.3 → XP_015316626.2  POU domain, class 2, transcription factor 1 isoform X3

    3. XM_015461135.3 → XP_015316621.2  POU domain, class 2, transcription factor 1 isoform X2

    4. XM_005203424.5 → XP_005203481.2  POU domain, class 2, transcription factor 1 isoform X1

      Related
      ENSBTAP00000085966.1, ENSBTAT00000111363.1

    5. XM_005203427.5 → XP_005203484.1  POU domain, class 2, transcription factor 1 isoform X5

      See identical proteins and their annotated locations for XP_005203484.1

      UniProtKB/TrEMBL
      A0A3Q1M3H3, A0A3Q1M487
      Related
      ENSBTAP00000064680.2, ENSBTAT00000086603.2
      Conserved Domains (2) summary
      smart00352
      Location:280 → 354
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:384 → 437
      Homeobox; Homeobox domain

    6. XM_059883669.1 → XP_059739652.1  POU domain, class 2, transcription factor 1 isoform X5

      UniProtKB/TrEMBL
      A0A3Q1M487

    7. XM_059883656.1 → XP_059739639.1  POU domain, class 2, transcription factor 1 isoform X4

      UniProtKB/TrEMBL
      F1MMF9
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.