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    PITX2 paired like homeodomain 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 487902, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PITX2provided by VGNC
    Official Full Name
    paired like homeodomain 2provided by VGNC
    Primary source
    VGNC:VGNC:44590
    See related
    Ensembl:ENSCAFG00845016014
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PITX2 in Genome Data Viewer
    Location:
    chromosome: 32
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 32 NC_051836.1 (30931178..30951191, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 32 NC_006614.4 (11306508..11326539)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 32 NC_049253.1 (9167168..9187192)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 32 NC_049292.1 (30916988..30937021, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 32 NC_049773.1 (30667533..30687592, complement)

    Chromosome 32 - NC_051836.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867205 Neighboring gene uncharacterized LOC111093616 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3-like Neighboring gene uncharacterized LOC102154537 Neighboring gene uncharacterized LOC119867164

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pituitary homeobox 2
    Names
    paired-like homeodomain transcription factor 2

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051836.1 Reference ROS_Cfam_1.0

      Range
      30931178..30951191 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038444383.1 → XP_038300311.1  pituitary homeobox 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PL96, A0A8P0P785
      Conserved Domains (2) summary
      pfam00046
      Location:43 → 96
      Homeobox; Homeobox domain
      pfam03826
      Location:229 → 246
      OAR; OAR domain

    2. XM_038444382.1 → XP_038300310.1  pituitary homeobox 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0R2W0, A0A8C0TNV7, A0A8I3NVW1
      Related
      ENSCAFP00845022442.1, ENSCAFT00845028528.1
      Conserved Domains (2) summary
      pfam00046
      Location:89 → 142
      Homeobox; Homeobox domain
      pfam03826
      Location:275 → 292
      OAR; OAR domain

    3. XM_038444381.1 → XP_038300309.1  pituitary homeobox 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0R2J8, A0A8C0TTG9, A0A8I3NZC0
      Related
      ENSCAFP00845022477.1, ENSCAFT00845028567.1
      Conserved Domains (3) summary
      COG5576
      Location:41 → 150
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:97 → 150
      Homeobox; Homeobox domain
      pfam03826
      Location:283 → 300
      OAR; OAR domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049292.1 Alternate UMICH_Zoey_3.1

      Range
      30916988..30937021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038518771.1 → XP_038374699.1  pituitary homeobox 2 isoform X3

      Conserved Domains (2) summary
      pfam00046
      Location:43 → 96
      Homeobox; Homeobox domain
      pfam03826
      Location:229 → 246
      OAR; OAR domain

    2. XM_038518770.1 → XP_038374698.1  pituitary homeobox 2 isoform X2

      Conserved Domains (2) summary
      pfam00046
      Location:89 → 142
      Homeobox; Homeobox domain
      pfam03826
      Location:275 → 292
      OAR; OAR domain

    3. XM_038518769.1 → XP_038374697.1  pituitary homeobox 2 isoform X1

      Conserved Domains (3) summary
      COG5576
      Location:41 → 150
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:97 → 150
      Homeobox; Homeobox domain
      pfam03826
      Location:283 → 300
      OAR; OAR domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049773.1 Alternate UNSW_CanFamBas_1.0

      Range
      30667533..30687592 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038646718.1 → XP_038502646.1  pituitary homeobox 2 isoform X3

      Conserved Domains (2) summary
      pfam00046
      Location:43 → 96
      Homeobox; Homeobox domain
      pfam03826
      Location:229 → 246
      OAR; OAR domain

    2. XM_038646717.1 → XP_038502645.1  pituitary homeobox 2 isoform X2

      Conserved Domains (2) summary
      pfam00046
      Location:89 → 142
      Homeobox; Homeobox domain
      pfam03826
      Location:275 → 292
      OAR; OAR domain

    3. XM_038646716.1 → XP_038502644.1  pituitary homeobox 2 isoform X1

      Conserved Domains (3) summary
      COG5576
      Location:41 → 150
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:97 → 150
      Homeobox; Homeobox domain
      pfam03826
      Location:283 → 300
      OAR; OAR domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049253.1 Alternate UU_Cfam_GSD_1.0

      Range
      9167168..9187192
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038581897.1 → XP_038437825.1  pituitary homeobox 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0R2W0, A0A8C0TNV7, A0A8I3NVW1
      Conserved Domains (2) summary
      pfam00046
      Location:89 → 142
      Homeobox; Homeobox domain
      pfam03826
      Location:275 → 292
      OAR; OAR domain

    2. XM_038581898.1 → XP_038437826.1  pituitary homeobox 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PL96, A0A8P0P785
      Conserved Domains (2) summary
      pfam00046
      Location:43 → 96
      Homeobox; Homeobox domain
      pfam03826
      Location:229 → 246
      OAR; OAR domain

    3. XM_038581896.1 → XP_038437824.1  pituitary homeobox 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0R2J8, A0A8C0TTG9, A0A8I3NZC0
      Conserved Domains (3) summary
      COG5576
      Location:41 → 150
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:97 → 150
      Homeobox; Homeobox domain
      pfam03826
      Location:283 → 300
      OAR; OAR domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006614.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      11306508..11326539
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003434038.5 → XP_003434086.1  pituitary homeobox 2 isoform X2

      See identical proteins and their annotated locations for XP_003434086.1

      UniProtKB/TrEMBL
      A0A8C0R2W0, A0A8C0TNV7, A0A8I3NVW1
      Conserved Domains (2) summary
      pfam00046
      Location:89 → 142
      Homeobox; Homeobox domain
      pfam03826
      Location:275 → 292
      OAR; OAR domain

    2. XM_003434039.5 → XP_003434087.1  pituitary homeobox 2 isoform X3

      See identical proteins and their annotated locations for XP_003434087.1

      UniProtKB/TrEMBL
      A0A8C0PL96, A0A8P0P785
      Conserved Domains (2) summary
      pfam00046
      Location:43 → 96
      Homeobox; Homeobox domain
      pfam03826
      Location:229 → 246
      OAR; OAR domain

    3. XM_846277.6 → XP_851370.1  pituitary homeobox 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0R2J8, A0A8C0TTG9, A0A8I3NZC0
      Conserved Domains (3) summary
      COG5576
      Location:41 → 150
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:97 → 150
      Homeobox; Homeobox domain
      pfam03826
      Location:283 → 300
      OAR; OAR domain
    Nucleotide Protein
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