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    Krt27 keratin 27 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 450229, updated on 5-Mar-2024

    Summary

    Official Symbol
    Krt27provided by RGD
    Official Full Name
    keratin 27provided by RGD
    Primary source
    RGD:1359115
    See related
    Ensembl:ENSRNOG00000011628 AllianceGenome:RGD:1359115
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ka40
    Summary
    Predicted to enable structural molecule activity. Predicted to act upstream of or within hair follicle morphogenesis. Predicted to be located in cytoplasm and intermediate filament. Orthologous to human KRT27 (keratin 27). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 40.4) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    10q31
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (84794848..84800131, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (84298684..84303967, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (87256434..87261717, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene keratin 25 Neighboring gene keratin 26 Neighboring gene uncharacterized LOC108352132 Neighboring gene keratin 28 Neighboring gene uncharacterized LOC134480872 Neighboring gene keratin 10

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in epithelial cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in hair follicle morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within hair follicle morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intermediate filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    keratin, type I cytoskeletal 27
    Names
    CK-27
    K27
    cytokeratin-27
    keratin 27, type I
    type I inner root sheath-specific keratin-K25irs3
    type I keratin KA40

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008824.1NP_001008824.1  keratin, type I cytoskeletal 27

      See identical proteins and their annotated locations for NP_001008824.1

      Status: PROVISIONAL

      Source sequence(s)
      BK004030
      UniProtKB/Swiss-Prot
      Q6IFW8
      UniProtKB/TrEMBL
      A6HIX6
      Related
      ENSRNOP00000015740.4, ENSRNOT00000015740.6
      Conserved Domains (2) summary
      pfam00038
      Location:73386
      Filament; Intermediate filament protein
      pfam11068
      Location:333376
      YlqD; YlqD protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      84794848..84800131 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)