map3k7.L mitogen-activated protein kinase kinase kinase 7 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: map3k7.L
Official Full Name: mitogen-activated protein kinase kinase kinase 7 L homeolog
Primary source: Xenbase:XB-GENE-481534
Locus tag: XELAEV_18027270mg
See related: EnsemblRapid:ENSXLAG00005027390
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: xTAK1; MAPKKK; map3k7
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 5L

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5L	NC_054379.1 (88566428..88610571)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5L	NC_030732.1 (86331531..86375678)

Chromosome 5L - NC_054379.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables MAP kinase kinase kinase activity	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within JNK cascade	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within immune response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mesoderm formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of receptor signaling pathway via STAT	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mitogen-activated protein kinase kinase kinase 7 L homeolog

Names: TAK1

NP_001084359.1

EC 2.7.11.25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090890.1 → NP_001084359.1 mitogen-activated protein kinase kinase kinase 7 L homeolog

See identical proteins and their annotated locations for NP_001084359.1

Status: PROVISIONAL

Source sequence(s)

U92030

UniProtKB/TrEMBL

A0A974CV78, A0A974HHH2, O73613

Related

ENSXLAP00005081471.1, ENSXLAT00005083082.1

Conserved Domains (2) summary

smart00219
Location:25 → 273

TyrKc; Tyrosine kinase, catalytic domain

cd14058
Location:31 → 281

STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1