EIF4A2 eukaryotic translation initiation factor 4A2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: EIF4A2provided by CGNC
Full Name: eukaryotic translation initiation factor 4A2provided by CGNC
Primary source: CGNC:49225
See related: Ensembl:ENSGALG00010016240
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: EIF4A1; EIF4AII; eIF4A-II; eIF-4A-II
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	9	NC_052540.1 (15898312..15905193)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	9	NC_052581.1 (15690771..15697654)

Chromosome 9 - NC_052540.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

study reports that interaction of the host eIF4AII with Infectious bursal disease virus (IBDV) VP1 inhibits the RNA polymerase activity of IBDV to reduce its replication in host cells
Title: Eukaryotic translational initiation factor 4AII reduces the replication of infectious bursal disease virus by inhibiting VP1 polymerase activity.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cytoplasmic translational initiation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasmic stress granule	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: eukaryotic initiation factor 4A-II

Names: ATP-dependent RNA helicase eIF4A-2; eukaryotic translation initiation factor 4A1; protein synthesis initiation factor 4AII; translational eukaryotic inititation factor 4AII

NP_989880.1

EC 3.6.4.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.