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    ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 [ Homo sapiens (human) ]

    Gene ID: 3708, updated on 30-Jun-2015
    Official Symbol
    ITPR1provided by HGNC
    Official Full Name
    inositol 1,4,5-trisphosphate receptor, type 1provided by HGNC
    Primary source
    HGNC:HGNC:6180
    See related
    Ensembl:ENSG00000150995; HPRD:00925; MIM:147265; Vega:OTTHUMG00000154996
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94
    Summary
    This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]
    Orthologs
    See ITPR1 in Epigenomics, MapViewer
    Location:
    3p26.1
    Exon count:
    63
    Annotation release Status Assembly Chr Location
    107 current GRCh38.p2 (GCF_000001405.28) 3 NC_000003.12 (4493348..4847840)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (4535032..4889524)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene sulfatase modifying factor 1 Neighboring gene mitochondrial ribosomal protein S10 pseudogene 2 Neighboring gene ITPR1 antisense RNA 1 (head to head) Neighboring gene uncharacterized LOC105376933 Neighboring gene uncharacterized LOC105376932 Neighboring gene eosinophil granule ontogeny transcript (non-protein coding) Neighboring gene BHLHE40 antisense RNA 1 Neighboring gene uncharacterized LOC105376934 Neighboring gene basic helix-loop-helix family, member e40

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NHGRI GWAS Catalog

    Description
    Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.
    NHGRI GWA Catalog
    Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
    NHGRI GWA Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    NHGRI GWA Catalog

    Protein interactions

    Protein Gene Interaction Pubs
    Nef nef HIV-1 Nef interacts with inositol 1,4,5-triphosphate receptor (IP3R) to trigger the activation of plasma membrane calcium influx channels PubMed
    Pr55(Gag) gag IP3R differentially associates with HIV-1 wild-type Gag and P7L-Gag, indicating that Gag and IP3R are in proximity at the plasma membrane PubMed
    gag Inositol (1,4,5)-triphosphate receptor (IP3R) function is required for efficient release of HIV-1 Gag PubMed
    gag SPRY-mediated inhibition of HIV-1 Gag release is repressed by IP3R PubMed
    Tat tat HIV-1 Tat induces release of calcium from inositol 1,4,5-triphosphate receptor-regulated stores in neurons and astrocytes, an effect that plays an important role in Tat-induced TNF-alpha production PubMed

    Go to the HIV-1, Human Interaction Database

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • DKFZp313E1334, DKFZp313N1434

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    calcium channel inhibitor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calcium ion transmembrane transporter activity TAS
    Traceable Author Statement
    more info
    PubMed 
    inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity TAS
    Traceable Author Statement
    more info
    PubMed 
    intracellular ligand-gated calcium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    phosphatidylinositol binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    Fc-epsilon receptor signaling pathway TAS
    Traceable Author Statement
    more info
     
    Fc-gamma receptor signaling pathway involved in phagocytosis TAS
    Traceable Author Statement
    more info
     
    activation of phospholipase C activity TAS
    Traceable Author Statement
    more info
     
    blood coagulation TAS
    Traceable Author Statement
    more info
     
    calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    calcium ion transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    endoplasmic reticulum calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    energy reserve metabolic process TAS
    Traceable Author Statement
    more info
     
    epidermal growth factor receptor signaling pathway TAS
    Traceable Author Statement
    more info
     
    fibroblast growth factor receptor signaling pathway TAS
    Traceable Author Statement
    more info
     
    innate immune response TAS
    Traceable Author Statement
    more info
     
    inositol phosphate-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
     
    inositol phosphate-mediated signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    inositol phosphate-mediated signaling TAS
    Traceable Author Statement
    more info
    PubMed 
    intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of calcium-mediated signaling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neurotrophin TRK receptor signaling pathway TAS
    Traceable Author Statement
    more info
     
    platelet activation TAS
    Traceable Author Statement
    more info
     
    post-embryonic development IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of insulin secretion TAS
    Traceable Author Statement
    more info
     
    release of sequestered calcium ion into cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to hypoxia IDA
    Inferred from Direct Assay
    more info
    PubMed 
    signal transduction NAS
    Non-traceable Author Statement
    more info
    PubMed 
    signal transduction TAS
    Traceable Author Statement
    more info
     
    small molecule metabolic process TAS
    Traceable Author Statement
    more info
     
    stimulatory C-type lectin receptor signaling pathway TAS
    Traceable Author Statement
    more info
     
    vascular endothelial growth factor receptor signaling pathway TAS
    Traceable Author Statement
    more info
     
    voluntary musculoskeletal movement IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    calcineurin complex IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum NAS
    Non-traceable Author Statement
    more info
    PubMed 
    endoplasmic reticulum membrane TAS
    Traceable Author Statement
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    platelet dense granule membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    platelet dense tubular network IDA
    Inferred from Direct Assay
    more info
    PubMed 
    platelet dense tubular network membrane TAS
    Traceable Author Statement
    more info
     
    postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
     
    sarcoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    inositol 1,4,5-trisphosphate receptor type 1
    Names
    IP3 receptor
    IP3R 1
    inositol 1,4,5-triphosphate receptor, type 1
    protein phosphatase 1, regulatory subunit 94
    type 1 InsP3 receptor
    type 1 inositol 1,4,5-trisphosphate receptor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016144.1 RefSeqGene

      Range
      5001..359493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001099952.2NP_001093422.2  inositol 1,4,5-trisphosphate receptor type 1 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AB208868, AK293752, AK309981, AW501800, BG202086, BM695661, BQ006717, DA060305, DB260851, L38019
      Consensus CDS
      CCDS46740.2
      UniProtKB/TrEMBL
      B4DER3
      UniProtKB/Swiss-Prot
      Q14643
      UniProtKB/TrEMBL
      Q59H91
      Related
      ENSP00000349597, OTTHUMP00000207084, ENST00000357086, OTTHUMT00000337979
      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22332423
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam00520
      Location:23202549
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19232035
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    2. NM_001168272.1NP_001161744.1  inositol 1,4,5-trisphosphate receptor type 1 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon, uses an alternate in-frame splice site and includes three additional exons in the central coding region, compared to variant 1, resulting in an isoform (3) that is longer than isoform 1.
      Source sequence(s)
      AB208868, AK293752, AK294594, BG202086, BQ006717, DA060305, DB260851, U23850
      Consensus CDS
      CCDS54551.1
      UniProtKB/TrEMBL
      B4DER3
      UniProtKB/TrEMBL
      B4DGH1
      UniProtKB/TrEMBL
      Q59H91
      Related
      ENSP00000306253, ENST00000302640
      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22662456
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam00520
      Location:23532582
      Ion_trans; Ion transport protein
      pfam01365
      Location:457662
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232418
      MIR; MIR domain
      pfam08454
      Location:19562068
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    3. NM_002222.5NP_002213.5  inositol 1,4,5-trisphosphate receptor type 1 isoform 2

      See identical proteins and their annotated locations for NP_002213.5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in a shorter isoform (2), compared to isoform 1.
      Source sequence(s)
      AB208868, AK293752, AK294594, BG202086, BQ006717, D26070, DA060305, DB260851
      Consensus CDS
      CCDS54550.1
      UniProtKB/TrEMBL
      B4DER3
      UniProtKB/TrEMBL
      B4DGH1
      UniProtKB/Swiss-Prot
      Q14643
      UniProtKB/TrEMBL
      Q59H91
      Related
      ENSP00000397885, OTTHUMP00000207085, ENST00000456211, OTTHUMT00000337980
      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22182408
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam00520
      Location:23052534
      Ion_trans; Ion transport protein
      pfam01365
      Location:457662
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232418
      MIR; MIR domain
      pfam08454
      Location:19082020
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p2 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p2 Primary Assembly

      Range
      4493348..4847840
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011533681.1XP_011531983.1  

      See identical proteins and their annotated locations for XP_011531983.1

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22822472
      COG1266; Predicted metal-dependent membrane protease [General function prediction only]
      pfam00520
      Location:23692598
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19722084
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    2. XM_011533690.1XP_011531992.1  

      Conserved Domains (6) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam00520
      Location:23282557
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19722084
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    3. XM_011533689.1XP_011531991.1  

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22452435
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam00520
      Location:23322561
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19722062
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    4. XM_011533683.1XP_011531985.1  

      See identical proteins and their annotated locations for XP_011531985.1

      Related
      ENSP00000346595, ENST00000354582
      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22812471
      COG1266; Predicted metal-dependent membrane protease [General function prediction only]
      pfam00520
      Location:23682597
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19712083
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    5. XM_011533685.1XP_011531987.1  

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22712461
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam00520
      Location:23582587
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19612073
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    6. XM_011533686.1XP_011531988.1  

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22702460
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam00520
      Location:23572586
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19602072
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    7. XM_006713131.2XP_006713194.1  

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22592449
      COG1266; Predicted metal-dependent membrane protease [General function prediction only]
      pfam00520
      Location:23462575
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19492061
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    8. XM_005265109.2XP_005265166.1  

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22582448
      COG1266; Predicted metal-dependent membrane protease [General function prediction only]
      pfam00520
      Location:23452574
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19482060
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    9. XM_005265110.2XP_005265167.1  

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22422432
      COG1266; Predicted metal-dependent membrane protease [General function prediction only]
      pfam00520
      Location:23292558
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19322044
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    10. XM_011533684.1XP_011531986.1  

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22732463
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam00520
      Location:23602589
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19632075
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    11. XM_011533687.1XP_011531989.1  

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22672457
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam00520
      Location:23542583
      Ion_trans; Ion transport protein
      pfam01365
      Location:457662
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232418
      MIR; MIR domain
      pfam08454
      Location:19572069
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    12. XM_011533688.1XP_011531990.1  

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22582448
      YdiL; Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones]
      pfam00520
      Location:23452574
      Ion_trans; Ion transport protein
      pfam01365
      Location:457662
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232418
      MIR; MIR domain
      pfam08454
      Location:19482060
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    13. XM_011533691.1XP_011531993.1  

      Conserved Domains (4) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    14. XM_011533692.1XP_011531994.1  

      Conserved Domains (4) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
    15. XM_011533682.1XP_011531984.1  

      See identical proteins and their annotated locations for XP_011531984.1

      Conserved Domains (7) summary
      smart00472
      Location:231287
      MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
      COG1266
      Location:22822472
      COG1266; Predicted metal-dependent membrane protease [General function prediction only]
      pfam00520
      Location:23692598
      Ion_trans; Ion transport protein
      pfam01365
      Location:472677
      RYDR_ITPR; RIH domain
      pfam02815
      Location:232433
      MIR; MIR domain
      pfam08454
      Location:19722084
      RIH_assoc; RyR and IP3R Homology associated
      pfam08709
      Location:4225
      Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

    Alternate CHM1_1.1

    Genomic

    1. NC_018914.2 Alternate CHM1_1.1

      Range
      4485103..4839760
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)