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    Slc38a11 solute carrier family 38, member 11 [ Mus musculus (house mouse) ]

    Gene ID: 320106, updated on 16-Apr-2024

    Summary

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    Official Symbol
    Slc38a11provided by MGI
    Official Full Name
    solute carrier family 38, member 11provided by MGI
    Primary source
    MGI:MGI:2443383
    See related
    Ensembl:ENSMUSG00000061171 AllianceGenome:MGI:2443383
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9330158F14Rik
    Summary
    Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to act upstream of or within amino acid transport and sodium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in cerebellum; ductus deferens; epididymis; ileum; and midbrain. Orthologous to human SLC38A11 (solute carrier family 38 member 11). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in adrenal adult (RPKM 1.8), bladder adult (RPKM 0.8) and 17 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    2 C1.3; 2 38.47 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (65144007..65194606, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (65313663..65364026, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene 13593 Neighboring gene STARR-positive B cell enhancer ABC_E2620 Neighboring gene STARR-seq mESC enhancer starr_04671 Neighboring gene microRNA 6337 Neighboring gene predicted gene, 24138

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Sour Sensing from the Tongue to the Brain. Zhang J, et al. Cell, 2019 Oct 3. PMID 31543264
    2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    3. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 
    • Endonuclease-mediated (3)  1 citation

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    putative sodium-coupled neutral amino acid transporter 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177074.2 → NP_796048.2  putative sodium-coupled neutral amino acid transporter 11

      See identical proteins and their annotated locations for NP_796048.2

      Status: VALIDATED

      Source sequence(s)
      AK139966, CJ055756
      Consensus CDS
      CCDS38129.1
      UniProtKB/Swiss-Prot
      A2ASI0, A2ASI1, Q3USY0
      UniProtKB/TrEMBL
      F6X0X3
      Related
      ENSMUSP00000108039.2, ENSMUST00000112420.8
      Conserved Domains (2) summary
      COG0814
      Location:39 → 413
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:32 → 420
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      65144007..65194606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162296.1 → XP_036018189.1  putative sodium-coupled neutral amino acid transporter 11 isoform X1

      UniProtKB/TrEMBL
      F6WJL8
      Conserved Domains (1) summary
      cl00456
      Location:32 → 398
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. XM_036162297.1 → XP_036018190.1  putative sodium-coupled neutral amino acid transporter 11 isoform X2

      Conserved Domains (1) summary
      cl00456
      Location:24 → 223
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    3. XM_036162298.1 → XP_036018191.1  putative sodium-coupled neutral amino acid transporter 11 isoform X3

      Conserved Domains (1) summary
      cl00456
      Location:1 → 192
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    4. XM_030251752.1 → XP_030107612.1  putative sodium-coupled neutral amino acid transporter 11 isoform X3

      Conserved Domains (1) summary
      cl00456
      Location:1 → 192
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3USY0.2 GenPept UniProtKB/Swiss-Prot:Q3USY0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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