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    Zfp276 zinc finger protein (C2H2 type) 276 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307924, updated on 5-Mar-2024

    Summary

    Official Symbol
    Zfp276provided by RGD
    Official Full Name
    zinc finger protein (C2H2 type) 276provided by RGD
    Primary source
    RGD:1307469
    See related
    Ensembl:ENSRNOG00000016631 AllianceGenome:RGD:1307469
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in kinetochore. Orthologous to human ZNF276 (zinc finger protein 276). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 71.6), Kidney (RPKM 67.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    Location:
    19q12
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (68199709..68212757)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (51291005..51304240)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (56054250..56067767)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene cyclin-dependent kinase 10 Neighboring gene spermatogenesis associated 2-like Neighboring gene VPS9 domain containing 1 Neighboring gene FA complementation group A Neighboring gene small nucleolar RNA SNORD43 Neighboring gene spire-type actin nucleation factor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      68199709..68212757
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002728603.7XP_002728649.1  zinc finger protein 276

      See identical proteins and their annotated locations for XP_002728649.1

      UniProtKB/TrEMBL
      F1LN08, Q6AXP9
      Related
      ENSRNOP00000022324.4
      Conserved Domains (3) summary
      smart00868
      Location:79155
      zf-AD; Zinc-finger associated domain (zf-AD)
      sd00017
      Location:467487
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:493515
      zf-C2H2; Zinc finger, C2H2 type

    RNA

    1. XR_005496931.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001012058.1: Suppressed sequence

      Description
      NM_001012058.1: This RefSeq was temporarily suppressed because the CDS was partial.