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    ABAT 4-aminobutyrate aminotransferase [ Bos taurus (cattle) ]

    Gene ID: 280969, updated on 3-Apr-2024

    Summary

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    Official Symbol
    ABATprovided by VGNC
    Official Full Name
    4-aminobutyrate aminotransferaseprovided by VGNC
    Primary source
    VGNC:VGNC:25454
    See related
    BGD:BT21049; Ensembl:ENSBTAG00000004038
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GABA-T; GABA-AT; L-AIBAT
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 25
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (7551557..7787339)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 114 Neighboring gene actin nucleation-promoting factor WASL-like Neighboring gene methyltransferase 22, Kin17 lysine Neighboring gene uncharacterized LOC132343839 Neighboring gene transmembrane protein 186 Neighboring gene phosphomannomutase 2 Neighboring gene calcium regulated heat stable protein 1 Neighboring gene LITAF domain containing Neighboring gene uncharacterized LOC112444343 Neighboring gene ubiquitin specific peptidase 7 Neighboring gene U6 spliceosomal RNA Neighboring gene HUWE1 associated protein modifying stress responses Neighboring gene microRNA mir-12003

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GABA-T in bovine medulla cells: kinetic properties and comparison with GABA-T from other tissues. Fernández-Ramil JM, et al. Rev Esp Fisiol, 1983 Sep. PMID 6658145
    2. Molecular cloning and functional expression of bovine brain GABA transaminase. Jeon SG, et al. Mol Cells, 2001 Aug 31. PMID 11561735

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC137464

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 4-aminobutyrate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gamma-aminobutyric acid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    4-aminobutyrate aminotransferase, mitochondrial
    Names
    (S)-3-amino-2-methylpropionate transaminase
    GABA aminotransferase
    GABA transaminase
    gamma-amino-N-butyrate transaminase
    NP_001075050.1
    XP_024840411.1
    XP_059737128.1
    XP_059737129.1
    XP_059737130.1
    XP_059737131.1
    XP_059737132.1
    XP_059737133.1
    XP_059737134.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081581.1 → NP_001075050.1  4-aminobutyrate aminotransferase, mitochondrial

      See identical proteins and their annotated locations for NP_001075050.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133277
      UniProtKB/TrEMBL
      A0A3Q1LII6, A2VDK2
      Related
      ENSBTAP00000005280.6, ENSBTAT00000005280.7
      Conserved Domains (2) summary
      TIGR00699
      Location:34 → 496
      GABAtrns_euk; 4-aminobutyrate aminotransferase, eukaryotic type
      COG0160
      Location:42 → 498
      GabT; 4-aminobutyrate aminotransferase or related aminotransferase [Amino acid transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      7551557..7787339
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059881150.1 → XP_059737133.1  4-aminobutyrate aminotransferase, mitochondrial isoform X2

    2. XM_059881151.1 → XP_059737134.1  4-aminobutyrate aminotransferase, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A8J8YN34, F1MFB7, M5FHM7

    3. XM_024984643.2 → XP_024840411.1  4-aminobutyrate aminotransferase, mitochondrial isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LII6, A0A8J8YN34, F1MFB7, M5FHM7
      Conserved Domains (1) summary
      TIGR00699
      Location:34 → 496
      GABAtrns_euk; 4-aminobutyrate aminotransferase, eukaryotic type

    4. XM_059881145.1 → XP_059737128.1  4-aminobutyrate aminotransferase, mitochondrial isoform X1

    5. XM_059881146.1 → XP_059737129.1  4-aminobutyrate aminotransferase, mitochondrial isoform X1

    6. XM_059881148.1 → XP_059737131.1  4-aminobutyrate aminotransferase, mitochondrial isoform X1

    7. XM_059881147.1 → XP_059737130.1  4-aminobutyrate aminotransferase, mitochondrial isoform X1

    8. XM_059881149.1 → XP_059737132.1  4-aminobutyrate aminotransferase, mitochondrial isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9BGI0.1 GenPept UniProtKB/Swiss-Prot:Q9BGI0

    Gene LinkOut

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