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    Rn18s 18S ribosomal RNA [ Mus musculus (house mouse) ]

    Gene ID: 19791, updated on 25-Jul-2023

    Summary

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    Official Symbol
    Rn18sprovided by MGI
    Official Full Name
    18S ribosomal RNAprovided by MGI
    Primary source
    MGI:MGI:97943
    See related
    AllianceGenome:MGI:97943
    Gene type
    rRNA
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    The sequences coding for ribosomal RNAs are present as rDNA repeating units distributed on chromosomes 12, 15, 16, 18 and 19. A 45S rRNA, which serves as the precursor for the 18S, 5.8S and 28S rRNA, is transcribed from each rDNA unit by RNA polymerase I. The number of rDNA repeating units varies between individuals and from chromosome to chromosome, although usually 30 to 40 repeats are found on each chromosome. These rDNA repeats are not currently annotated on the reference genome. This gene represents the portion of one rDNA repeat which encodes a 18S rRNA. [provided by RefSeq, Jan 2014]
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    chromosome: 6

    Bibliography

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    Related articles in PubMed

    1. VELCRO-IP RNA-seq reveals ribosome expansion segment function in translation genome-wide. Leppek K, et al. Cell Rep, 2021 Jan 19. PMID 33472078, Free PMC Article
    2. 3-Nitropropionic acid modifies neurotrophin mRNA expression in the mouse striatum: 18S-rRNA is a reliable control gene for studies of the striatum. Espíndola S, et al. Neurosci Bull, 2012 Oct. PMID 22961474, Free PMC Article
    3. Probing the structure of mouse Ehrlich ascites cell 5.8S, 18S and 28S ribosomal RNA in situ. Holmberg L, et al. Nucleic Acids Res, 1994 Apr 25. PMID 8190627, Free PMC Article
    4. Complete nucleotide sequence of mouse 18 S rRNA gene: comparison with other available homologs. Raynal F, et al. FEBS Lett, 1984 Feb 27. PMID 6365592
    5. Retroposons do jump: a B2 element recently integrated in an 18S rDNA gene. Oberbäumer I. Nucleic Acids Res, 1992 Feb 25. PMID 1311830, Free PMC Article

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Homozygous CINAP-/- mice show embryonic lethality. The heterozygotes are viable and show defects in 18S rRNA processing.
      Title: The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth.
    2. 18S-rRNA is a reliable control gene for measuring neurotrophin mRNA expression following neuronal damage produced by inhibition of mitochondrial respiration.
      Title: 3-Nitropropionic acid modifies neurotrophin mRNA expression in the mouse striatum: 18S-rRNA is a reliable control gene for studies of the striatum.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Other Names

    • 18S RNA

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_003278.3 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      BK000964
    Nucleotide Protein Strain
    Heading Accession and Version

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