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    MUC5AC mucin 5AC, oligomeric mucus/gel-forming [ Sus scrofa (pig) ]

    Gene ID: 110259210, updated on 15-Mar-2024

    Summary

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    Official Symbol
    MUC5ACprovided by VGNC
    Official Full Name
    mucin 5AC, oligomeric mucus/gel-formingprovided by VGNC
    Primary source
    VGNC:VGNC:90483
    See related
    Ensembl:ENSSSCG00000033382
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Biased expression in lung (RPKM 3.8), mixtures (RPKM 1.5) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    49
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 2 NC_010444.4 (757897..790321)

    Chromosome 2 - NC_010444.4Genomic Context describing neighboring genes Neighboring gene mucin 6, oligomeric mucus/gel-forming Neighboring gene mucin 2, oligomeric mucus/gel-forming Neighboring gene mucin 5B, oligomeric mucus/gel-forming Neighboring gene toll interacting protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_010444.4 Chromosome 2 Reference Sscrofa11.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. A Rheological Study of the Association and Dynamics of MUC5AC Gels. Wagner CE, et al. Biomacromolecules, 2017 Nov 13. PMID 28903557, Free PMC Article
    2. Cysteine-rich regions of pig gastric mucin contain von willebrand factor and cystine knot domains at the carboxyl terminal(1). Turner BS, et al. Biochim Biophys Acta, 1999 Oct 6. PMID 10500247
    3. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: mucin-5AC
    Names
    gastric mucin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010444.4 Reference Sscrofa11.1 Primary Assembly

      Range
      757897..790321
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021082583.1 → XP_020938242.1  LOW QUALITY PROTEIN: mucin-5AC

      UniProtKB/TrEMBL
      A0A8W4FM62
      Related
      ENSSSCP00000079988.1, ENSSSCT00000097005.1
      Conserved Domains (9) summary
      smart00041
      Location:5688 → 5768
      CT; C-terminal cystine knot-like domain (CTCK)
      smart00214
      Location:5441 → 5499
      VWC; von Willebrand factor (vWF) type C domain
      smart00215
      Location:394 → 439
      VWC_out; von Willebrand factor (vWF) type C domain
      smart00216
      Location:891 → 1050
      VWD; von Willebrand factor (vWF) type D domain
      smart00832
      Location:622 → 692
      C8; This domain contains 8 conserved cysteine residues
      pfam01826
      Location:336 → 392
      TIL; Trypsin Inhibitor like cysteine rich domain
      pfam08742
      Location:5305 → 5364
      C8; C8 domain
      pfam13330
      Location:1870 → 1957
      Mucin2_WxxW; Mucin-2 protein WxxW repeating region
      cl26464
      Location:1470 → 1556
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein
    Heading Accession and Version

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