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    Alas2 5'-aminolevulinate synthase 2 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100721933, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Alas2
    Gene description
    5'-aminolevulinate synthase 2
    See related
    Ensembl:ENSCPOG00000007268
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947486.1 (27242472..27264930, complement)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176249.1 (1465976..1488336)

    NW_026947486.1Genomic Context describing neighboring genes Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene protein VCF1-like Neighboring gene protein VCF1-like Neighboring gene Ras related GTP binding B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 5-aminolevulinate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in erythrocyte development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heme biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hemoglobin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5-aminolevulinate synthase, erythroid-specific, mitochondrial
    Names
    aminolevulinate, delta-, synthase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947486.1 Reference mCavPor4.1

      Range
      27242472..27264930 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003461750.5 → XP_003461798.1  5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform X1

      UniProtKB/TrEMBL
      H0V9P7
      Related
      ENSCPOP00000006548.2
      Conserved Domains (3) summary
      COG0156
      Location:143 → 544
      BioF; 7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]
      TIGR01821
      Location:143 → 548
      5aminolev_synth; 5-aminolevulinic acid synthase
      pfam09029
      Location:5 → 100
      Preseq_ALAS; 5-aminolevulinate synthase presequence

    2. XM_063245965.1 → XP_063102035.1  5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform X2

    Nucleotide Protein
    Heading Accession and Version

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