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    Zfand3 zinc finger, AN1-type domain 3 [ Mus musculus (house mouse) ]

    Gene ID: 21769, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Zfand3provided by MGI
    Official Full Name
    zinc finger, AN1-type domain 3provided by MGI
    Primary source
    MGI:MGI:1096572
    See related
    Ensembl:ENSMUSG00000044477 AllianceGenome:MGI:1096572
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tex27; TEG-27
    Summary
    Predicted to enable DNA binding activity and zinc ion binding activity. Orthologous to human ZFAND3 (zinc finger AN1-type containing 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 72.1), subcutaneous fat pad adult (RPKM 35.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    17 A3.3; 17 15.59 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (30224013..30429797)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (30005039..30210823)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene MAM domain containing glycosylphosphatidylinositol anchor 1 Neighboring gene predicted gene, 41559 Neighboring gene STARR-seq mESC enhancer starr_42301 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:30116968-30117151 Neighboring gene predicted gene, 22327 Neighboring gene predicted gene, 53994 Neighboring gene tubulin alpha, related sequence 1 Neighboring gene STARR-seq mESC enhancer starr_42304 Neighboring gene BTB domain containing 9 Neighboring gene predicted gene, 25049 Neighboring gene ribosomal protein S17 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Tex27, a gene containing a zinc-finger domain, is up-regulated during the haploid stages of spermatogenesis. de Luis O, et al. Exp Cell Res, 1999 Jun 15. PMID 10366431
    2. Examining the specificity of Src homology 3 domain--ligand interactions with alkaline phosphatase fusion proteins. Yamabhai M, et al. Anal Biochem, 1997 Apr 5. PMID 9126384
    3. Tex261, a novel gene presumably related but distinct from steroidogenic acute regulatory (StAR) gene, is regulated during the development of germ cells. López-Fernández LA, et al. Biochem Biophys Res Commun, 1998 Jan 26. PMID 9464256
    4. Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. López-Fernández LA, et al. Mamm Genome, 1996 Sep. PMID 8703127
    5. Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. Tkatchenko TV, et al. Physiol Genomics, 2009 Nov 6. PMID 19723774, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC103362, MGC118625

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    AN1-type zinc finger protein 3
    Names
    testis-expressed protein 27

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356265.1 → NP_001343194.1  AN1-type zinc finger protein 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC125044, BC083124, BC100559, CV561920
      Consensus CDS
      CCDS89053.1
      UniProtKB/Swiss-Prot
      Q497H0, Q8K230, Q8R2V7, Q8R3V1
      Related
      ENSMUSP00000154782.2, ENSMUST00000226208.3
      Conserved Domains (2) summary
      pfam01428
      Location:160 → 194
      zf-AN1; AN1-like Zinc finger
      pfam01754
      Location:19 → 36
      zf-A20; A20-like zinc finger

    2. NM_148926.3 → NP_683728.1  AN1-type zinc finger protein 3 isoform 1

      See identical proteins and their annotated locations for NP_683728.1

      Status: VALIDATED

      Source sequence(s)
      AC125044, BC083124, CV561920
      Consensus CDS
      CCDS28598.1
      UniProtKB/Swiss-Prot
      Q497H0
      Related
      ENSMUSP00000063158.8, ENSMUST00000057897.10
      Conserved Domains (3) summary
      PLN02328
      Location:46 → 136
      PLN02328; lysine-specific histone demethylase 1 homolog
      pfam01754
      Location:19 → 36
      zf-A20; A20-like zinc finger
      pfam01428
      Location:138 → 172
      zf-AN1; AN1-like Zinc finger

    RNA

    1. NR_151442.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC125044, AK082915, BC083124, CV561920

    2. NR_151443.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC125044, AK148316, BC083124, CV561920
      Related
      ENSMUST00000226421.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      30224013..30429797
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524028.2 → XP_006524091.1  AN1-type zinc finger protein 3 isoform X1

      Conserved Domains (1) summary
      pfam01428
      Location:153 → 173
      zf-AN1; AN1-like Zinc finger
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q497H0.1 GenPept UniProtKB/Swiss-Prot:Q497H0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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