CXCL11 C-X-C motif chemokine ligand 11 [Sus scrofa (pig)] - Gene

Summary

Official Symbol: CXCL11provided by VGNC
Official Full Name: C-X-C motif chemokine ligand 11provided by VGNC
Primary source: VGNC:VGNC:87102
See related: Ensembl:ENSSSCG00000008978
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Ubiquitous expression in lung (RPKM 3.0), mixtures (RPKM 2.0) and 7 other tissues See more
Orthologs: human all
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Genomic context

Location:: chromosome: 8

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	8	NC_010450.4 (71713790..71725669, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	8	NC_010450.3 (75909581..75921427, complement)

Chromosome 8 - NC_010450.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

cloning and characterization of expressed gene sequences of the interferon-gamma inducible chemokine CXCL11, or I-TAC, associated with type 1 T-helper immune responses
Title: Expressed gene sequence and bioactivity of the IFNgamma-response chemokine CXCL11 of swine and cattle.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CXCR chemokine receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables chemokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to lipopolysaccharide	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neutrophil chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-X-C motif chemokine 11

Names: chemokine C-X-C motif ligand 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001128491.1 → NP_001121963.1 C-X-C motif chemokine 11 precursor

See identical proteins and their annotated locations for NP_001121963.1

Status: PROVISIONAL

Source sequence(s)

EU682377

UniProtKB/TrEMBL

B3GDY9

Conserved Domains (1) summary

cd00273
Location:28 → 90

Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

NC_010450.4 Reference Sscrofa11.1 Primary Assembly

Range

71713790..71725669 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005666774.3 → XP_005666831.1 C-X-C motif chemokine 11 isoform X1

See identical proteins and their annotated locations for XP_005666831.1

UniProtKB/TrEMBL

A0A4X1SX03, A0A8D1B9F1, F1RYT7

Related

ENSSSCP00000009580.2, ENSSSCT00000009833.6

Conserved Domains (1) summary

cd00273
Location:28 → 90

Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...