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    MAFB MAF bZIP transcription factor B [ Homo sapiens (human) ]

    Gene ID: 9935, updated on 5-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MAFB shapes human monocyte-derived macrophage response to SARS-CoV-2 and controls severe COVID-19 biomarker expression.

    MAFB shapes human monocyte-derived macrophage response to SARS-CoV-2 and controls severe COVID-19 biomarker expression.
    Simón-Fuentes M, Ríos I, Herrero C, Lasala F, Labiod N, Luczkowiak J, Roy-Vallejo E, Fernández de Córdoba-Oñate S, Delgado-Wicke P, Bustos M, Fernández-Ruiz E, Colmenares M, Puig-Kröger A, Delgado R, Vega MA, Corbí ÁL, Domínguez-Soto Á., Free PMC Article

    01/3/2024
    Reversal of MYB-dependent suppression of MAFB expression overrides leukaemia phenotype in MLL-rearranged AML.

    Reversal of MYB-dependent suppression of MAFB expression overrides leukaemia phenotype in MLL-rearranged AML.
    Negri A, Ward C, Bucci A, D'Angelo G, Cauchy P, Radesco A, Ventura AB, Walton DS, Clarke M, Mandriani B, Pappagallo SA, Mondelli P, Liao K, Gargano G, Zaccaria GM, Viggiano L, Lasorsa FM, Ahmed A, Di Molfetta D, Fiermonte G, Cives M, Guarini A, Vegliante MC, Ciavarella S, Frampton J, Volpe G., Free PMC Article

    12/1/2023
    Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB.

    Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB.
    de la Aleja AG, Herrero C, Torres-Torresano M, Schiaffino MT, Del Castillo A, Alonso B, Vega MA, Puig-Kröger A, Castrillo A, Corbí ÁL., Free PMC Article

    04/19/2023
    MafB-dependent neurotransmitter signaling promotes beta cell migration in the developing pancreas.

    MafB-dependent neurotransmitter signaling promotes β cell migration in the developing pancreas.
    Bsharat S, Monni E, Singh T, Johansson JK, Achanta K, Bertonnier-Brouty L, Schmidt-Christensen A, Holmberg D, Kokaia Z, Prasad RB, Artner I., Free PMC Article

    03/28/2023
    Misexpression of LINC01410, FOSL1, and MAFB in peripheral blood mononuclear cells associated with diabetic nephropathy.

    Misexpression of LINC01410, FOSL1, and MAFB in peripheral blood mononuclear cells associated with diabetic nephropathy.
    Asadollahi S, Hadizadeh M, Namiranian N, Kalantar SM, Firoozabadi AD, Injinari N.

    03/7/2023
    Podocyte-specific Transcription Factors: Could MafB Become a Therapeutic Target for Kidney Disease?

    Podocyte-specific Transcription Factors: Could MafB Become a Therapeutic Target for Kidney Disease?
    Morito N, Usui T, Ishibashi S, Yamagata K., Free PMC Article

    01/14/2023
    Circ_0051079 functions as an oncogenic regulator in osteosarcoma by leading to MAFB expression upregulation by competitively interacting with miR-1286.

    Circ_0051079 functions as an oncogenic regulator in osteosarcoma by leading to MAFB expression upregulation by competitively interacting with miR-1286.
    Huang Z, Chen P, Jia R, Liu Y., Free PMC Article

    10/15/2022
    GPBAR1 promotes proliferation and is related to poor prognosis of high-grade glioma via inducing MAFB expression.

    GPBAR1 promotes proliferation and is related to poor prognosis of high-grade glioma via inducing MAFB expression.
    Sun S, Guo H, Liang N, Wu T, Zhang C, Li H.

    06/18/2022
    Repression of Mafb promotes foreskin fibroblast proliferation through upregulation of CDK2, cyclin E and PCNA.

    Repression of Mafb promotes foreskin fibroblast proliferation through upregulation of CDK2, cyclin E and PCNA.
    Kong X, Liu Z, Long C, Shen L, Liu X, Wei G.

    06/18/2022
    MAFB promotes the malignant phenotypes by IGFBP6 in esophageal squamous cell carcinomas.

    MAFB promotes the malignant phenotypes by IGFBP6 in esophageal squamous cell carcinomas.
    Zhang S, Gong T, Nan Y, Feng R, Liu Z, Chen H.

    05/7/2022
    Duane retraction syndrome characterized by inner ear agenesis and neurodevelopmental phenotype in an Italian family with a variant in MAFB.

    Duane retraction syndrome characterized by inner ear agenesis and neurodevelopmental phenotype in an Italian family with a variant in MAFB.
    Pascolini G, Passarelli C, Lipari M, Chandramouli B, Chillemi G, Di Giosaffatte N, Novelli A, Grammatico P.

    04/30/2022
    Coordinated glucocorticoid receptor and MAFB action induces tolerogenesis and epigenome remodeling in dendritic cells.

    Coordinated glucocorticoid receptor and MAFB action induces tolerogenesis and epigenome remodeling in dendritic cells.
    Morante-Palacios O, Ciudad L, Micheroli R, de la Calle-Fabregat C, Li T, Barbisan G, Houtman M, Edalat SG, Frank-Bertoncelj M, Ospelt C, Ballestar E., Free PMC Article

    02/19/2022
    Expression of Mafb is down-regulated in the foreskin of children with hypospadias.

    Expression of Mafb is down-regulated in the foreskin of children with hypospadias.
    Kong X, Luo J, Xiang H, Wang S, Shen L, Long C, Liu F, Lin T, He D, Liu X, Wei GH.

    08/21/2021
    Transcription factor MafB in podocytes protects against the development of focal segmental glomerulosclerosis.

    Transcription factor MafB in podocytes protects against the development of focal segmental glomerulosclerosis.
    Usui T, Morito N, Shawki HH, Sato Y, Tsukaguchi H, Hamada M, Jeon H, Yadav MK, Kuno A, Tsunakawa Y, Okada R, Ojima T, Kanai M, Asano K, Imamura Y, Koshida R, Yoh K, Usui J, Yokoi H, Kasahara M, Yoshimura A, Muratani M, Kudo T, Oishi H, Yamagata K, Takahashi S.

    08/7/2021
    Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis.

    Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis.
    Dieterich LC, Tacconi C, Menzi F, Proulx ST, Kapaklikaya K, Hamada M, Takahashi S, Detmar M., Free PMC Article

    07/10/2021
    MicroRNA-148a facilitates inflammatory dendritic cell differentiation and autoimmunity by targeting MAFB.

    MicroRNA-148a facilitates inflammatory dendritic cell differentiation and autoimmunity by targeting MAFB.
    Meng Y, Li J, Ye Z, Yin Z, Sun Q, Liao Z, Li G, Deng J, Liu L, Yu Y, Wu L, Zhou H, Shen N., Free PMC Article

    05/22/2021
    MAFB and MAF Transcription Factors as Macrophage Checkpoints for COVID-19 Severity.

    MAFB and MAF Transcription Factors as Macrophage Checkpoints for COVID-19 Severity.
    Vega MA, Simón-Fuentes M, González de la Aleja A, Nieto C, Colmenares M, Herrero C, Domínguez-Soto Á, Corbí ÁL., Free PMC Article

    01/2/2021
    Identification of a novel mutation in the MAFB gene in a pediatric patient with multicentric carpotarsal osteolysis syndrome using next-generation sequencing.

    Identification of a novel mutation in the MAFB gene in a pediatric patient with multicentric carpotarsal osteolysis syndrome using next-generation sequencing.
    Li J, Shi L, Lau K, Ma Y, Jia S, Gao X.

    01/2/2021
    Association between MAFB rs17820943 and rs6072081 polymorphism and risk of nonsyndromic cleft lip with or without cleft palate: a meta-analysis.

    Association between MAFB rs17820943 and rs6072081 polymorphism and risk of nonsyndromic cleft lip with or without cleft palate: a meta-analysis.
    Liang X, Huang L, Ou Y, He Y, Tang S.

    12/26/2020
    miR-155 Knockdown Protects against Cerebral Ischemia and Reperfusion Injury by Targeting MafB.

    miR-155 Knockdown Protects against Cerebral Ischemia and Reperfusion Injury by Targeting MafB.
    Zhang L, Liu C, Huang C, Xu X, Teng J., Free PMC Article

    11/28/2020
    MAFB Promotes Cancer Stemness and Tumorigenesis in Osteosarcoma through a Sox9-Mediated Positive Feedback Loop.

    MAFB Promotes Cancer Stemness and Tumorigenesis in Osteosarcoma through a Sox9-Mediated Positive Feedback Loop.
    Chen Y, Wang T, Huang M, Liu Q, Hu C, Wang B, Han D, Chen C, Zhang J, Li Z, Liu C, Lei W, Chang Y, Wu M, Xiang D, Chen Y, Wang R, Huang W, Lei Z, Chu X.

    11/21/2020
    The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.

    The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.
    He Y, Wang S, Tong J, Jiang S, Yang Y, Zhang Z, Xu Y, Zeng Y, Cao B, Moran MF, Mao X., Free PMC Article

    10/24/2020
    Loss of the transcription factor MAFB limits beta-cell derivation from human PSCs.

    Loss of the transcription factor MAFB limits β-cell derivation from human PSCs.
    Russell R, Carnese PP, Hennings TG, Walker EM, Russ HA, Liu JS, Giacometti S, Stein R, Hebrok M., Free PMC Article

    08/22/2020
    MAFB was expressed in tumor-associated macrophages in human lung cancer samples, and can be used to assess tumor malignancy.

    Transcription factor MafB is a marker of tumor-associated macrophages in both mouse and humans.
    Yadav MK, Inoue Y, Nakane-Otani A, Tsunakawa Y, Jeon H, Samir O, Teramoto A, Kulathunga K, Kusakabe M, Nakamura M, Kudo T, Takahashi S, Hamada M.

    08/1/2020
    Study in two unrelated families with Focal Segmental Glomerulosclerosis associated with Duane Retraction Syndrome revealed that affected individuals harbor a rare heterozygous substitution (p.Leu239Pro) in MAFB, a leucine zipper transcription factor.

    A mutation in transcription factor MAFB causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome.
    Sato Y, Tsukaguchi H, Morita H, Higasa K, Tran MTN, Hamada M, Usui T, Morito N, Horita S, Hayashi T, Takagi J, Yamaguchi I, Nguyen HT, Harada M, Inui K, Maruta Y, Inoue Y, Koiwa F, Sato H, Matsuda F, Ayabe S, Mizuno S, Sugiyama F, Takahashi S, Yoshimura A.

    06/1/2019
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